Matrix vesicles (MVs) are well positioned in the growth plate to serve as a carrier of
morphogenetic information to nearby chondrocytes and osteoblasts. Bone morphogenetic …

Matrix vesicles (MtVs) are one of the extracellular vesicles (EVs) secreted by osteoblasts.
Although MtVs have a classically-defined function as an initiator of ossification and recent …

Abstract Background Matrix vesicles (MVs) are released from hypertrophic chondrocytes
and from mature osteoblasts, the cells responsible for endochondral and membranous …

Many key processes central to bone formation and homeostasis require the involvement of
osteoblasts, cells responsible for accumulation and mineralization of the extracellular matrix …

Matrix vesicles (MV) play a key role in the initiation of cartilage mineralization. Although
many components in these microstructures have been identified, the specific function of …

The importance of matrix vesicles (MVs) has been repeatedly highlighted in the formation of
cartilage, bone, and dentin since their discovery in 1967. These nano-vesicular structures …

Calcifying matrix vesicles (MVs) are released from chondrocytes and osteoblasts in
monolayer culture. In the present studies, we tested the ability of rachitic versus normal rat …

Matrix vesicles have a critical role in the initiation of mineral deposition in skeletal tissues,
but the ways in which they exert this key function remain poorly understood. This issue is …

In bone, mineralization is tightly regulated by osteoblasts and hypertrophic chondrocytes
which release matrix vesicles (MVs) and control extracellular ionic conditions and matrix …

Mineralizing matrix vesicles (MVs) are extracellular organelles produced by chondrocytes,
osteoblasts, and odontoblasts under physiological conditions and by vascular smooth …