[HTML][HTML] Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision …

A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …

[HTML][HTML] New frontiers in metabolomics: from measurement to insight

E Riekeberg, R Powers - F1000Research, 2017 - ncbi.nlm.nih.gov
Metabolomics is the newest addition to the “omics” disciplines and has shown rapid growth
in its application to human health research because of fundamental advancements in …

Metabolomics as a truly translational tool for precision medicine

JC Schmidt, BV Dougherty, RD Beger… - … journal of toxicology, 2021 - journals.sagepub.com
Metabolomics is unique among omics technologies in being applicable to metabolism and
toxicity studies broadly across organisms (eg, humans, other mammals, model organisms …

Biomarker discovery and translation in metabolomics

GA Nagana Gowda, D Raftery - Current Metabolomics, 2013 - ingentaconnect.com
The multifaceted field of metabolomics has witnessed exponential growth in both methods
development and applications. Owing to the urgent need, a significant fraction of research …

[HTML][HTML] Current status of metabolomic biomarker discovery: impact of study design and demographic characteristics

V Tolstikov, AJ Moser, R Sarangarajan, NR Narain… - Metabolites, 2020 - mdpi.com
Widespread application of omic technologies is evolving our understanding of population
health and holds promise in providing precise guidance for selection of therapeutic …

Metabolomics in the clinic: A review of the shared and unique features of untargeted metabolomics for clinical research and clinical testing

AD Kennedy, BM Wittmann, AM Evans… - Journal of Mass …, 2018 - Wiley Online Library
Metabolomics is the untargeted measurement of the metabolome, which is composed of the
complement of small molecules detected in a biological sample. As such, metabolomic …

Toward the implementation of metabolomic assessments of human health and nutrition

SM Watkins, JB German - Current Opinion in Biotechnology, 2002 - Elsevier
Metabolomics is emerging as an exciting post-genomic science with applications that span
the scope of biotechnology and medicine. Although metabolomics is still in its infancy, it has …

Metabolomics: an emerging but powerful tool for precision medicine

CB Clish - Molecular Case Studies, 2015 - molecularcasestudies.cshlp.org
Metabolomics, which is defined as the comprehensive analysis of metabolites in a biological
specimen, is an emerging technology that holds promise to inform the practice of precision …

Exploring disease through metabolomics

N Vinayavekhin, EA Homan… - ACS chemical biology, 2010 - ACS Publications
Metabolomics approaches provide an analysis of changing metabolite levels in biological
samples. In the past decade, technical advances have spurred the application of …

Metabolomics analysis for biomarker discovery: advances and challenges

MS Monteiro, M Carvalho, ML Bastos… - Current medicinal …, 2013 - ingentaconnect.com
Over the last decades there has been a change in biomedical research with the search for
single genes, transcripts, proteins, or metabolites being substituted by the coverage of the …