Metabolomics as a key integrator for “omic” advancement of personalized medicine and future therapies

AD Eckhart, K Beebe, M Milburn - Clinical and translational …, 2012 - Wiley Online Library
Investigation into biological complexity, whether for a better understanding of disease or
drug process, is a monumental task plaguing investigators. The lure of “omic” technologies …

Getting the right answers: understanding metabolomics challenges

S Beisken, M Eiden, RM Salek - Expert review of molecular …, 2015 - Taylor & Francis
Small molecules within biological systems provide powerful insights into the biological roles,
processes and states of organisms. Metabolomics is the study of the concentrations …

Modern analytical techniques in metabolomics analysis

A Zhang, H Sun, P Wang, Y Han, X Wang - Analyst, 2012 - pubs.rsc.org
Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …

Metabolomics analytics workflow for epidemiological research: perspectives from the consortium of metabolomics studies (COMETS)

MC Playdon, AD Joshi, FK Tabung, S Cheng… - Metabolites, 2019 - mdpi.com
The application of metabolomics technology to epidemiological studies is emerging as a
new approach to elucidate disease etiology and for biomarker discovery. However, analysis …

The evolving landscape of untargeted metabolomics

A Di Minno, M Gelzo, M Stornaiuolo… - Nutrition, Metabolism …, 2021 - Elsevier
Abstract Aims Untargeted Metabolomics is a “hypothesis-generating discovery strategy” that
compares groups of samples (eg, cases vs controls); identifies the metabolome and …

Metabolomics as a challenging approach for medicinal chemistry and personalized medicine

M Frederich, B Pirotte, M Fillet… - Journal of medicinal …, 2016 - ACS Publications
“Omics” sciences have been developed to provide a holistic point of view of biology and to
better understand the complexity of an organism as a whole. These systems biology …

Current metabolomics: practical applications

SP Putri, Y Nakayama, F Matsuda, T Uchikata… - Journal of bioscience …, 2013 - Elsevier
The field of metabolomics continues to grow rapidly over the last decade and has been
proven to be a powerful technology in predicting and explaining complex phenotypes in …

Metabolomics: basic principles and strategies

S Nalbantoglu - Molecular medicine, 2019 - books.google.com
Metabolomics is the study of metabolome within cells, biofluids, tissues, or organisms to
comprehensively identify and quantify all endogenous and exogenous low-molecular …

Metabolomics

K Burgess, N Rankin, S Weidt - Handbook of pharmacogenomics …, 2014 - eprints.gla.ac.uk
Metabolomics is a recently developed technique for the analysis of the small-molecule
component of biological systems and samples. Metabolites consist of a very heterogeneous …

Metabolomics in biomarker discovery: future uses for cancer prevention

YS Kim, P Maruvada, JA Milner - Future Oncology, 2008 - Taylor & Francis
Metabolomics is the systematic study of small-molecular-weight substances in cells, tissues
and/or whole organisms as influenced by multiple factors including genetics, diet, lifestyle …