Moving molecules: mRNA trafficking in Mammalian oligodendrocytes and neurons
R Smith - The Neuroscientist, 2004 - journals.sagepub.com
Numerous mRNA molecules are localized in regions of the dendrites of neurons, some
moving along dendrites in response to synaptic activity. The proteins encoded by these …
moving along dendrites in response to synaptic activity. The proteins encoded by these …
Cytoplasmic and nuclear localization of myelin basic proteins reveals heterogeneity among oligodendrocytes
RJ Hardy, RA Lazzarini, DR Colman… - Journal of …, 1996 - Wiley Online Library
Myelin basic proteins (MBPs) are major proteins of central nervous system (CNS) myelin,
where they facilitate the apposition of cytoplasmic faces of myelin lamellae. Myelin‐bearing …
where they facilitate the apposition of cytoplasmic faces of myelin lamellae. Myelin‐bearing …
Neuronal RNA‐binding protein dysfunction in multiple sclerosis cortex
HE Salapa, C Hutchinson, BF Popescu… - Annals of Clinical and …, 2020 - Wiley Online Library
Objective Neurodegeneration is thought to be the primary cause of neurological disability in
multiple sclerosis (MS). Dysfunctional RNA‐binding proteins (RBPs) including their …
multiple sclerosis (MS). Dysfunctional RNA‐binding proteins (RBPs) including their …
Neuronal BC1 RNA: intracellular transport and activity-dependent modulation
J Brosius, H Tiedge - Cell polarity and subcellular RNA localization, 2001 - Springer
RNA transport in dendrites, and subsequent local translation in postsynaptic micro domains,
have increasingly been recognized as potentially powerful tools for neurons in long-term …
have increasingly been recognized as potentially powerful tools for neurons in long-term …
Neuronal RNA‐binding proteins in health and disease
SC Lenzken, T Achsel, MT Carrì… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
In mammalian cells in general and in neurons in particular, mRNA maturation, translation,
and degradation are highly complex and dynamic processes. RNA‐binding proteins (RBPs) …
and degradation are highly complex and dynamic processes. RNA‐binding proteins (RBPs) …
Myelin-associated oligodendrocytic basic protein mRNAs reside at different subcellular locations.
RM Gould, CM Freund… - Journal of …, 1999 - search.ebscohost.com
Abstract: The mRNAs for two myelin proteins, myelin basic protein (MBP) and myelin-
associated oligodendrocytic basic protein (MOBP)-81A, are uniquely located at sites where …
associated oligodendrocytic basic protein (MOBP)-81A, are uniquely located at sites where …
hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis
A Iervolino, G Santilli, R Trotta, C Guerzoni… - … and cellular biology, 2002 - Am Soc Microbiol
Abstract hnRNP A1 is a nucleocytoplasmic shuttling heterogeneous nuclear
ribonucleoprotein that accompanies eukaryotic mRNAs from the active site of transcription to …
ribonucleoprotein that accompanies eukaryotic mRNAs from the active site of transcription to …
RNA binding proteins accumulate at the postsynaptic density with synaptic activity
G Zhang, TA Neubert, BA Jordan - Journal of Neuroscience, 2012 - Soc Neuroscience
Neuronal activity elicits changes in synaptic composition that play an important role in
experience-dependent plasticity (;;;). We used a modified version of stable isotope labeling …
experience-dependent plasticity (;;;). We used a modified version of stable isotope labeling …
Dendritic targeting of short and long 3′ UTR BDNF mRNA is regulated by BDNF or NT-3 and distinct sets of RNA-binding proteins
A Vicario, A Colliva, A Ratti, L Davidovic… - Frontiers in molecular …, 2015 - frontiersin.org
Sorting of mRNAs in neuronal dendrites relies upon inducible transport mechanisms whose
molecular bases are poorly understood. We investigated here the mechanism of inducible …
molecular bases are poorly understood. We investigated here the mechanism of inducible …
Interactions of noncanonical motifs with hnRNP A2 promote activity-dependent RNA transport in neurons
A key determinant of neuronal functionality and plasticity is the targeted delivery of select
ribonucleic acids (RNAs) to synaptodendritic sites of protein synthesis. In this paper, we ask …
ribonucleic acids (RNAs) to synaptodendritic sites of protein synthesis. In this paper, we ask …