Spatiotemporal translational regulation plays a key role in determining cell fate and function.
Specifically, in neurons, local translation in dendrites is essential for synaptic plasticity and …

To achieve accurate spatiotemporal patterns of gene expression, RNA-binding proteins
(RBPs) guide nuclear processing, intracellular trafficking and local translation of target …

As neurons are one of the most highly polarized cells in our body, they require sophisticated
cellular mechanisms to maintain protein homeostasis in their subcellular compartments such …

Dendritic protein synthesis plays a critical role in several forms of synaptic plasticity,
including BDNF (brain-derived neurotrophic factor)-mediated long-term synaptic potentiation …

Liquid–liquid phase separation results in the formation of dynamic biomolecular
condensates, also known as membrane-less organelles, that allow for the assembly of …

The RNA-binding protein hnRNP Q has been implicated in neuronal mRNA metabolism.
Here, we show that knockdown of hnRNP Q increased neurite complexity in cultured rat …

Several mRNAs are known to be targeted to dendrites in hippocampal neurons. In this study,
we show that brain-derived neurotrophic factor (BDNF) mRNA has two distinct cis-acting …

mRNA localization provides polarized cells with a locally renewable source of proteins. In
neurons, mRNA translation can occur at millimeters to centimeters from the cell body, giving …

Neural BC1 RNA is distributed in dendrites in the form of ribonucleoprotein particles (RNP).
Recently, Hanet al. reported that testis-brain RNA-binding protein (the mouse homologue of …

In neural cells, certain RNAs are targeted to dendrites by a specific RNA trafficking pathway,
termed the A2 pathway, mediated by the trans‐acting trafficking factor, heterogeneous …