The time is ripe to harmonize global acute febrile illness etiologic investigations

J Moreira, BL Fernando-Carballo, C Escadafal… - medRxiv, 2022 - medrxiv.org
Acute febrile illness (AFI) is common for people seeking care globally and represents a
spectrum of infectious and non-infectious etiologies with significant geographical variations …

Prioritising pathogens for the management of severe febrile patients to improve clinical care in low-and middle-income countries

J Osborn, T Roberts, E Guillen, O Bernal… - BMC Infectious …, 2020 - Springer
Background Severe febrile illness without a known source (SFWS) is a challenge for
clinicians when deciding how to manage a patient, particularly given the wide spectrum of …

Diagnostic tools used in the evaluation of acute febrile illness in South India: a scoping review

D Bhaskaran, SS Chadha, S Sarin, R Sen… - BMC infectious …, 2019 - Springer
Background Acute febrile illness (AFI) is characterized by malaise, myalgia and a raised
temperature that is a nonspecific manifestation of infectious diseases in the tropics. The lack …

Host biomarkers to predict the severity of acute febrile illness: A scoping review

ML Robinson, M Workneh, S Dittrich, S Kurlekar, R Yee… - medRxiv, 2019 - medrxiv.org
Background Acute febrile illness (AFI) ranges from mild to mortal, yet severity is difficult to
assess. Host biomarkers may identify patients with AFI who require a higher level of care; …

The association between the degree of fever as measured in the emergency department and clinical outcomes of hospitalized adult patients

E Marcusohn, I Gibory, A Miller, AM Lipsky… - The American Journal of …, 2022 - Elsevier
Background Fever is a physiologic response to a wide range of pathologies and one of the
most common complaints and clinical signs in the emergency medicine department (ED) …

Global knowledge gaps in acute febrile illness etiologic investigations: A scoping review

C Rhee, GA Kharod, N Schaad… - PLoS neglected …, 2019 - journals.plos.org
Background Acute febrile illness (AFI), a common reason for people seeking medical care
globally, represents a spectrum of infectious disease etiologies with important variations …

Acute undifferentiated febrile illness: Protocol in emergency department

VN Subramanyam, N Kaeley, M Kumar… - Journal of Family …, 2020 - journals.lww.com
Fever accounts for around 15% of emergency visits in elderly age group and around 5% in
adults. The spectrum of etiologies ranges from non-infectious to infectious etiologies. There …

Impact of a package of diagnostic tools, clinical algorithm, and training and communication on outpatient acute fever case management in low-and middle-income …

O Salami, P Horgan, CE Moore, A Giri, A Sserwanga… - Trials, 2020 - Springer
Background The management of acute febrile illnesses places a heavy burden on clinical
services in many low-and middle-income countries (LMICs). Bacterial and viral aetiologies …

[HTML][HTML] Distinguishing bacterial versus non-bacterial causes of febrile illness–a systematic review of host biomarkers

BL Fernandez-Carballo, C Escadafal, E MacLean… - Journal of Infection, 2021 - Elsevier
Abstract Background Acute febrile illnesses (AFIs) represent a major disease burden
globally; however, the paucity of reliable, rapid point-of-care testing makes their diagnosis …

Addressing Acute Febrile Illness Using a Syndromic Approach During A Chikungunya Epidemic in Rio de Janeiro, Brazil: A Prospective Observational Study

J Moreira, BL Fernandez-Carballo, C Escadafal… - medRxiv, 2023 - medrxiv.org
Background Identifying etiologies of acute febrile illness (AFI) is challenging in settings with
limited laboratory capacity. We aimed to describe the causes of AFI among non-severe …