Background Genes specifically expressed in the oocyte play key roles in oogenesis, ovarian
folliculogenesis, fertilization and/or early embryonic development. In an attempt to identify …

Female infertility syndromes are among the most prevalent chronic health disorders in
women, but their genetic basis remains unknown because of uncertainty regarding the …

An oocyte's journey is highly distinct from the vast majority of cells in the body. As one of the
largest and rarest cells, oocytes express unique genes required for the genesis of healthy …

Cross-phylum and cross-species comparative transcriptomic analyses provide an
evolutionary perspective on how specific tissues use genomic information. A significant …

The identification of genes and deduced pathways from the mature human oocyte can help
us better understand oogenesis, folliculogenesis, fertilization, and embryonic development …

The oocyte is a key regulator of ovarian folliculogenesis and early embryonic development.
However, the composition of the oocyte transcriptome and identities and functions of key …

Ovary development is a complex process involving numerous genes. A well-developed
ovary is essential for females to keep fertility and reproduce offspring. In order to gain a …

Background Previously, we have demonstrated that genes involved in ovarian function are
highly conserved throughout evolution. In this study, we aimed to document the conservation …

Background The initial stages of development depend on mRNA and proteins accumulated
in the oocyte, and during these stages, certain genes are essential for fertilization, first …

This work presents a systematic approach to study the conservation of genes between fruit
flies and mammals. We have listed 971 Drosophila genes involved in female reproduction at …