Restless legs syndrome: a comprehensive overview on its epidemiology, risk factors, and treatment

P Yeh, AS Walters, JW Tsuang - Sleep and Breathing, 2012 - Springer
Purposes Restless legs syndrome (RLS) is underdiagnosed and poorly understood by
clinicians and the general public alike; accordingly, a broad literature review with …

Restless legs syndrome: a clinical update

CE Gamaldo, CJ Earley - Chest, 2006 - Elsevier
Restless legs syndrome (RLS) is a common and often disabling sensorimotor disorder.
Epidemiologic studies suggest that RLS is an underrecognized and undertreated disorder …

[HTML][HTML] Restless legs syndrome

M Bayard, T Avonda, J Wadzinski - American family physician, 2008 - aafp.org
Restless legs syndrome is a common neurologic movement disorder that affects
approximately 10 percent of adults. Of those affected with this condition, approximately one …

[HTML][HTML] The management of restless legs syndrome: an updated algorithm

MH Silber, MJ Buchfuhrer, CJ Earley, BB Koo… - Mayo Clinic …, 2021 - Elsevier
Restless legs syndrome (RLS) is a common disorder. The population prevalence is 1.5% to
2.7% in a subgroup of patients having more severe RLS with symptoms occurring 2 or more …

Pharmacologic therapy for primary restless legs syndrome: a systematic review and meta-analysis

TJ Wilt, R MacDonald, J Ouellette… - JAMA internal …, 2013 - jamanetwork.com
Importance Restless legs syndrome (RLS) is a neurological disorder characterized by
unpleasant sensations in the legs and a distressing, irresistible urge to move them. We …

Restless legs syndrome and periodic leg movements of sleep

DB Rye, LM Trotti - Neurologic clinics, 2012 - Elsevier
Women are more commonly affected than men by restless legs syndrome, and prevalence is
highest amongst those of northern European heritage. The motor manifestations include …

Diagnosis, comorbidities, and management of restless legs syndrome

PM Becker, M Novak - Current medical research and opinion, 2014 - Taylor & Francis
Objective: This narrative review describes the differential diagnosis of restless legs
syndrome, and provides an overview of the evidence for the associations between RLS and …

[HTML][HTML] Restless legs syndrome: from pathophysiology to clinical diagnosis and management

S Guo, J Huang, H Jiang, C Han, J Li, X Xu… - Frontiers in aging …, 2017 - frontiersin.org
Restless legs syndrome (RLS), a common neurological sensorimotor disorder in western
countries, has gained more and more attention in Asian countries. The prevalence of RLS is …

[HTML][HTML] Restless legs syndrome across the lifespan: symptoms, pathophysiology, management and daily life impact of the different patterns of disease presentation

G Didato, R Di Giacomo, GJ Rosa, A Dominese… - International Journal of …, 2020 - mdpi.com
Restless legs syndrome is a common but still underdiagnosed neurologic disorder,
characterized by peculiar symptoms typically occurring in the evening and at night, and …

Restless legs syndrome: update on pathogenesis

Y Dauvilliers, J Winkelmann - Current opinion in pulmonary …, 2013 - journals.lww.com
RLS is a genetically heterogeneous complex trait with high prevalence but large phenotype
variability. Current theories of RLS pathophysiology emphasize brain iron deficiency with …