[HTML][HTML] Erlotinib in advanced non-small cell lung cancer: efficacy and safety findings of the global phase IV Tarceva Lung Cancer Survival Treatment study
M Reck, N van Zandwijk, C Gridelli, Z Baliko… - Journal of Thoracic …, 2010 - Elsevier
Introduction: Erlotinib is a small molecule inhibitor of epidermal growth factor receptor
tyrosine-kinase activity that has been shown to significantly increase survival for patients …
tyrosine-kinase activity that has been shown to significantly increase survival for patients …
Second-line erlotinib in patients with advanced non-small-cell lung cancer: subgroup analyses from the TRUST study
DF Heigener, YL Wu, N van Zandwijk, P Mali… - Lung Cancer, 2011 - Elsevier
Erlotinib is a highly potent inhibitor of epidermal growth factor receptor tyrosine-kinase
activity that significantly prolongs overall survival in patients with non-small-cell lung cancer …
activity that significantly prolongs overall survival in patients with non-small-cell lung cancer …
Erlotinib for frontline treatment of advanced non–small cell lung cancer: a phase II study
G Giaccone, M Gallegos Ruiz, T Le Chevalier… - Clinical Cancer …, 2006 - AACR
Purpose: Erlotinib has proven activity in pretreated patients with advanced non–small cell
lung cancer (NSCLC). We evaluated erlotinib in the frontline treatment of advanced NSCLC …
lung cancer (NSCLC). We evaluated erlotinib in the frontline treatment of advanced NSCLC …
Final survival and safety results from a multicenter, open‐label, phase 3b trial of erlotinib in patients with advanced nonsmall cell lung cancer
DR Spigel, M Lin, V O'Neill… - … International Journal of …, 2008 - Wiley Online Library
BACKGROUND. Erlotinib is an orally available, reversible inhibitor of epidermal growth
factor receptor (EGFR) with a proven survival advantage for patients with locally advanced …
factor receptor (EGFR) with a proven survival advantage for patients with locally advanced …
[HTML][HTML] Efficacy and safety of erlotinib monotherapy for Japanese patients with advanced non-small cell lung cancer: a phase II study
K Kubota, Y Nishiwaki, T Tamura, K Nakagawa… - Journal of Thoracic …, 2008 - Elsevier
Introduction The aim of this study was to evaluate the efficacy and safety of Erlotinib in
Japanese patients with previously treated non-small cell lung cancer (NSCLC). Available …
Japanese patients with previously treated non-small cell lung cancer (NSCLC). Available …
An expanded access program of erlotinib (Tarceva) in patients with advanced non-small cell lung cancer (NSCLC): data report from Italy
M Tiseo, C Gridelli, S Cascinu, L Crinò, FV Piantedosi… - Lung Cancer, 2009 - Elsevier
BACKGROUND: Erlotinib demonstrated significantly prolonged survival versus placebo in
patients with advanced NSCLC who had progressed after standard chemotherapy. TRUST …
patients with advanced NSCLC who had progressed after standard chemotherapy. TRUST …
[HTML][HTML] Erlotinib in previously treated non–small-cell lung cancer
FA Shepherd, J Rodrigues Pereira… - New England journal …, 2005 - Mass Medical Soc
Background We conducted a randomized, placebo-controlled, double-blind trial to
determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs survival …
determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs survival …
[HTML][HTML] Efficacy and safety of erlotinib in 1242 East/South-East Asian patients with advanced non-small cell lung cancer
T Mok, Y Wu, JS Au, C Zhou, L Zhang, RP Perng… - Journal of Thoracic …, 2010 - Elsevier
Introduction: Erlotinib is an epidermal growth factor receptor tyrosine kinase inhibitor that
significantly increases survival for patients with previously treated advanced non-small cell …
significantly increases survival for patients with previously treated advanced non-small cell …
[HTML][HTML] Postmarketing surveillance study of erlotinib in Japanese patients with non–small-cell lung cancer (NSCLC): an interim analysis of 3488 patients …
K Nakagawa, S Kudoh, Y Ohe, T Johkoh… - Journal of Thoracic …, 2012 - Elsevier
Introduction: Interstitial lung disease (ILD) is an adverse drug reaction (ADR) of concern in
Japanese patients with non–small-cell lung cancer (NSCLC) receiving erlotinib. To …
Japanese patients with non–small-cell lung cancer (NSCLC) receiving erlotinib. To …
[PDF][PDF] Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non–small-cell lung cancer: The Tarceva Lung Cancer Investigation Trial
U Gatzemeier, A Pluzanska, A Szczesna… - Journal of Clinical …, 2007 - researchgate.net
Purpose Erlotinib is a potent inhibitor of the epidermal growth factor receptor tyrosine kinase,
with single-agent antitumor activity. Preclinically, erlotinib enhanced the cytotoxicity of …
with single-agent antitumor activity. Preclinically, erlotinib enhanced the cytotoxicity of …
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