Premedication with oral midazolam in children—an assessment of psychomotor function, anxiolysis, sedation and pharmacokinetics

RDM Jones, AR Visram, JP Kornberg… - … and intensive care, 1994 - journals.sagepub.com
We studied 30 children, aged 4 to 12 years, undergoing elective circumcision, premedicated
with midazolam 0.5 mg. kg− 1 and atropine 0.02 mg. kg− 1 by mouth. A modified postbox …

Premedication of children with oral midazolam

CO McMillan, IA Spahr-Schopfer, N Sikich… - Canadian Journal of …, 1992 - Springer
In a randomized, double-blind, placebo-controlled study, the safety, efficacy and feasibility of
oral midazolam premedication in children were evaluated in an ambulatory surgery unit …

Midazolam premedication in children: a comparison of two oral dosage formulations on sedation score and plasma midazolam levels

KK Brosius, CF Bannister - Anesthesia & Analgesia, 2003 - journals.lww.com
We compared two available oral formulations of midazolam with respect to sedation score
and plasma midazolam levels in pediatric surgical patients 2–10 yr old. The commercially …

Premedication with midazolam in young children: a comparison of four routes of administration

A Kogan, J Katz, R Efrat, LA Eidelman - Pediatric Anesthesia, 2002 - Wiley Online Library
Background: We undertook a study to determine the effects of four routes of administation on
the efficacy of midazolam for premedication. Methods: In a randomized double‐blind study …

Oral administration of midazolam as a premedicant for paediatric day‐case anaesthesia

A McCluskey, GH Meakin - Anaesthesia, 1994 - Wiley Online Library
Summary Fifty‐four children aged 1–10 years, scheduled for day‐case anaesthesia were
prescribed either oral midazolam 0.5 mg. kg‐1 or a placebo preparation 30‐60 min pre …

Oral midazolam premedication for paediatric day case patients

SH Cray, JL Dixon, CMB Heard… - Pediatric …, 1996 - Wiley Online Library
Forty‐nine children having day‐stay surgical procedures were randomly assigned to receive
oral midazolam 0.75 mg· kg− 1 or placebo in a double blind fashion. The child's level of …

Rectal, oral and nasal premedication using midazolam in children aged 1-6 years. A comparative clinical study

W Tolksdorf, C Eick - Der Anaesthesist, 1991 - europepmc.org
Midazolam is often used for the premedication of children in the pre-school age group.
Different noninvasive routes of administration have been described. In a prospective study …

Induction of general anesthesia in children with midazolam--is there an induction dose?

M Salonen, J Kanto, E Iisalo - International Journal of Clinical …, 1987 - europepmc.org
The pharmacodynamics of midazolam was studied in 27 children undergoing elective
surgery at five different dose levels (0.075-0.6 mg/kg) in attempting to find a suitable …

Oral midazolam in children: effect of time and adjunctive therapy

BC Weldon, MF Watcha, PF White - Anesthesia & Analgesia, 1992 - journals.lww.com
The purpose of this study was to determine the influence of timing and concomitant
administration of atropine and/or meperidine on the perioperative effects of oral midazolam …

Premedication with midazolam in children. Effect of intranasal, rectal and oral routes on plasma midazolam concentrations

JM Malinovsky, C Populaire, A Cozian… - …, 1995 - Wiley Online Library
We report a study performed to compare the time and plasma drug concentrations
necessary to achieve a similar state of sedation after midazolam premedication given by …