Per-and post-remote ischemic conditioning attenuates ischemic brain injury via inhibition of the TLR4/MyD88 signaling pathway in aged rats

J Lv, W Yan, J Zhou, H Pei, R Zhao - Experimental Brain Research, 2021 - Springer
Remote ischemic conditioning (RIC), as an emerging protective method, might be used
clinically to prevent ischemia–reperfusion injury (IRI) in ischemic stroke. In this study, we aim …

Remote ischemic postconditioning protects ischemic brain from injury in rats with focal cerebral ischemia/reperfusion associated with suppression of TLR4 and NF-кB …

W Qi, F Zhou, S Li, Y Zong, M Zhang, Y Lin, X Zhang… - …, 2016 - journals.lww.com
Remote ischemic postconditioning (RIPC) has been proven to be a promising protective
method for brain damage caused by transient focal ischemia/reperfusion (I/R) injury …

Remote ischemic postconditioning protects the brain from focal ischemia/reperfusion injury by inhibiting autophagy through the mTOR/p70S6K pathway

G Chen, X Shan, X Li, H Tao - Neurological research, 2018 - Taylor & Francis
Abstract Objective: Remote ischemic postconditioning (RIPostC) has been recognized as an
applicable strategy for protecting against cerebral ischemia/reperfusion (I/R) injury. This …

[HTML][HTML] The potential mechanism and clinical application value of remote ischemic conditioning in stroke

Y Zhu, X Li, X Lei, L Tang, D Wen, B Zeng… - Neural Regeneration …, 2025 - journals.lww.com
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning
against stroke. Although numerous animal researches have shown that the neuroprotective …

[HTML][HTML] Neuroprotection by remote ischemic conditioning in the setting of acute ischemic stroke: a preclinical two-centre study

MV Basalay, M Wiart, F Chauveau, C Dumot, C Leon… - Scientific Reports, 2020 - nature.com
Reperfusion is the only existing strategy for patients with acute ischemic stroke, however it
causes further brain damage itself. A feasible therapy targeting reperfusion injury is remote …

Neuroprotection by remote ischemic conditioning in rodent models of focal ischemia: a systematic review and meta-analysis

AJ Ripley, MS Jeffers, MW McDonald, J Montroy… - Translational Stroke …, 2021 - Springer
Remote ischemic conditioning (RIC) is a promising neuroprotective therapy for ischemic
stroke. Preclinical studies investigating RIC have shown RIC reduced infarct volume, but …

Remote limb ischemic postconditioning protects mouse brain against cerebral ischemia/reperfusion injury via upregulating expression of Nrf2, HO-1 and NQO-1 in …

P Li, L Su, X Li, W Di, X Zhang, C Zhang… - International Journal …, 2016 - Taylor & Francis
Remote ischemic postconditioning (RIPostC) is a promising therapeutic intervention, which
has been discovered to reduce ischemia/reperfusion (I/R) injury in heart, kidney, brain and …

[HTML][HTML] Effects of different remote ischemia perconditioning methods on cerebral infarct volume and neurological impairment in rats

S Otsuka, Y Itashiki, A Tani, T Matsuoka, S Takada… - Scientific reports, 2023 - nature.com
Remote ischemic perconditioning (RIPerC) is a novel neuroprotective method against
cerebral infarction that has shown efficacy in animal studies but has not been consistently …

Remote ischaemic perconditioning reduces the infarct volume and improves the neurological function of acute ischaemic stroke partially through the miR-153-5p …

H Zha, W Miao, W Rong, A Wang, W Jiang, R Liu… - Folia …, 2021 - termedia.pl
Remote ischemic perconditioning (RIPerC) could improve neuronal damage and inhibit
inflammation and apoptosis. We conducted an in-depth exploration of the protective …

[HTML][HTML] Remote ischemic conditioning attenuates oxidative stress and inflammation via the Nrf2/HO-1 pathway in MCAO mice

YY Sun, HJ Zhu, RY Zhao, SY Zhou, MQ Wang, Y Yang… - Redox biology, 2023 - Elsevier
The protective effects of remote ischemic conditioning (RIC) on acute ischemic stroke have
been reported. However, the protective mechanisms of RIC have not been fully elucidated …