Bridging the gap between academic research and regulatory health risk assessment of endocrine disrupting chemicals

A Beronius, A Hanberg, J Zilliacus, C Rudén - Current opinion in …, 2014 - Elsevier
Highlights•The use of academic research in risk assessment of EDCs needs to be
improved.•Regulatory risk assessment puts specific requirements on study design and …

Using systematic reviews for hazard and risk assessment of endocrine disrupting chemicals

A Beronius, LN Vandenberg - Reviews in Endocrine and Metabolic …, 2015 - Springer
The possibility that endocrine disrupting chemicals (EDCs) in our environment contribute to
hormonally related effects and diseases observed in human and wildlife populations has …

Endocrine disruptor global policy

CD Kassotis, L Trasande - Advances in pharmacology, 2021 - Elsevier
Over the past several decades, scientific consensus has grown around the concept and
evidence for human health impacts from exposure to endocrine disrupting chemicals …

[HTML][HTML] Risk assessment of endocrine active chemicals: Identifying chemicals of regulatory concern

R Bars, I Fegert, M Gross, D Lewis, L Weltje… - Regulatory Toxicology …, 2012 - Elsevier
The European regulation on plant protection products (1107/2009)(EC, 2009a), the
revisions to the biocides Directive (COM [2009] 267)(EC, 2009b), and the regulation …

A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals

LN Vandenberg, M Ågerstrand, A Beronius… - Environmental …, 2016 - Springer
Background The issue of endocrine disrupting chemicals (EDCs) is receiving wide attention
from both the scientific and regulatory communities. Recent analyses of the EDC literature …

Toxicity testing and endocrine disrupting chemicals

LN Vandenberg - Advances in Pharmacology, 2021 - Elsevier
Regulatory agencies around the world depend on standardized testing approaches to
evaluate environmental chemicals for endocrine disrupting properties. The US …

Why endocrine disrupting chemicals (EDCs) challenge traditional risk assessment and how to respond

VF Fuhrman, A Tal, S Arnon - Journal of hazardous materials, 2015 - Elsevier
Endocrine disrupting compounds (EDCs) are a diverse group of “chemicals of emerging
concern” which have attracted much interest from the research community since the 1990s …

Advancing Endocrine Disruptors via In Vitro Evaluation: Recognizing the Significance of the Organization for Economic Co-Operation and Development and United …

S Fouyet, MC Ferger, P Leproux, P Rat, M Dutot - Toxics, 2024 - mdpi.com
Efforts are being made globally to improve the evaluation and understanding of endocrine-
disrupting chemicals. Recognition of their impact on human health and the environment has …

Perspective on health effects of endocrine disruptors with a focus on data gaps

RE FitzGerald - Chemical research in toxicology, 2020 - ACS Publications
Screening for endocrine disrupting properties at the molecular and cellular level is
developing rapidly, but can epidemiology bridge the gap to human health impact? Reviews …

Principles of pharmacology and toxicology also govern effects of chemicals on the endocrine system

H Autrup, FA Barile, BJ Blaauboer… - Toxicological …, 2015 - academic.oup.com
The present debate on chemicals with Hormonal activity, often termed 'endocrine disruptors',
is highly controversial and includes challenges of the present paradigms used in toxicology …