Burst-forming unit-erythroid (BFU-E) and colony-forming unit-erythroid (CFU-E) cells are
erythroid progenitors traditionally defined by colony assays. We developed a flow cytometry …

The effects of recombinant human erythropoietin (rEp) on murine hematopoietic progenitors
were studied using a serum-free culture. A high concentration of rEp stimulated the …

The addition of thrombopoietin (TPO) to HEL cells, cultured in a chemically defined serum-
free medium, induced a rapid and dose-dependent phosphorylation of the transcription …

Differentiation of mouse marrow megakaryocyte progenitors (CFUm) was studied in vitro by
a colony assay using a plasma clot system. Erythropoietin (EPO) from sheep plasma (6 …

We evaluated the effects of human thrombopoietin (TPO) alone, or in combination with other
several hematopoietic factors, on megakaryocyte colony growth from human umbilical cord …

The relationship between major histocompatibility complex class II antigens (MHC class II,
eg, HLA-DR, Ia), T lymphocytes, and the enhancement of erythroid colony formation from …

OBJECTIVE: Although the anticancer activities of histone deacetylase (HDAC) inhibitors
have been studied, a role for HDAC in normal hematopoiesis has not been clearly defined …

We developed an efficient differentiation induction system (OP9 system) from mouse
embryonic stem (ES) cell to blood cells by coculture on a novel stromal cell line, OP9. This …

Determining the developmental pathway leading to erythrocytes and being able to isolate
their progenitors are crucial to understanding and treating disorders of red cell imbalance …

Two classes of human marrow megakaryocyte progenitor cells are described. Colony-
forming unit-megakaryocyte (CFU-MK)-derived colonies appeared in vitro after 12-day …