Two major signaling pathways, those triggered by estrogen (E 2) and by the Wnt family,
interact in the breast to cause growth and differentiation. The estrogen receptors ER α and …

Estrogen receptors (ERs), which mediate the proliferative action of estrogens in breast
cancer cells, are ligand-dependent transcription factors that regulate expression of their …

We have used a series of human estrogen receptor (ER) mutants to evaluate the cell-and
promoter-specific transcriptional activities of the TAF1 and TAF2 transactivation regions …

Estrogen-responsive genes are regulated by altering the balance of estrogen receptor (ER)
interaction with transcription activators and inhibitors. Here we examined the role of ER …

Estrogen receptors (ERs), which mediate estrogen actions, regulate cell growth and
differentiation of a variety of normal tissues and hormone-responsive tumors through …

Accumulating evidence indicates that estrogen regulates diverse but interdependent
signaling pathways via estrogen receptor (ER)-dependent and-independent mechanisms …

Transcription initiation at eukaryotic protein-coding gene promoters is regulated by a
complex interplay of site-specific DNA-binding proteins acting synergistically or …

The use of reverse genetics has permitted a definition of the structural features within
estrogen receptor required for its productive association with the transcription apparatus …

The human estrogen receptor (hER) is expressed in breast cancer MCF-7 cells and plays a
major role in tumorigenic processes. In this report, we demonstrate that MCF-7-specific …

The estrogen response element (ERE) directly linked to a TATA box induces CAT activity in
a hormone-dependent manner in Fe 33 cells, the rat hepatoma cell line FTO-2B, stably …