Microphthalmia‐associated transcription factor (MITF) plays a pivotal role in melanocyte
survival and differentiation. Nevertheless, until now it has not been possible to show that …

Microphthalmia transcription factor (MITF) positively regulates transcription of differentiation‐
related genes in several cell lineages, including melanocytes. Recent data also indicate a …

Melanocyte and retinal pigment epithelium (RPE) specifically express tyrosinase and other
melanin‐producing enzymes. Microphthalmia‐associated transcription factor (Mitf), encoded …

Microphthalmia-associated transcription factor (MITF), the human homolog of the mouse
microphthalmia gene product, regulates melanocyte-specific transcription of the tyrosinase …

The gene residing at the microphthalmia locus that causes white and small eye phenotype
in mice when mutated was cloned and named microphthalmia-associated transcription …

Since its discovery over a decade ago, the microphthalmia-associated transcription factor
(MITF), has moved ever more to the center of pigment cell biology. Not only has MITF been …

Mutations at the mouse locus encoding microphthalmia-associated transcription factor (Mitf)
affect the development of many cell types, including retinal pigment epithelium (RPE) …

Microphthalmia‐associated transcription factor (MITF) was initially shown to play a key role
in melanocyte differentiation through the direct transcriptional control of TYROSINASE …

MITF and pigmentation play important roles in both normal melanocyte and transformed
melanoma cell biology. MITF is regulated by many pathways and it also regulates many …

We transfected the melanocyte-specific Mitf-M isoform into the aggressive melanoma UISO-
Mel-6 cell lines. Our data show that Mitf decreases cell proliferation and results in cells …