Efficacy of concurrent chemoradiotherapy with S-1 vs radiotherapy alone for older patients with esophageal cancer: a multicenter randomized phase 3 clinical trial

Y Ji, X Du, W Zhu, Y Yang, J Ma, L Zhang, J Li… - JAMA …, 2021 - jamanetwork.com
Importance Most older patients with esophageal cancer cannot complete the standard
concurrent chemoradiotherapy (CCRT). An effective and tolerable chemoradiotherapy …

Patterns of care and locoregional treatment outcomes in older esophageal cancer patients: The SEER-Medicare Cohort

GL Smith, BD Smith, TA Buchholz, Z Liao… - International Journal of …, 2009 - Elsevier
PURPOSE: Optimal management of elderly patients with nonmetastatic esophageal cancer
is unclear. Patterns of care and long-term outcome data after locoregional treatment …

Definitive chemoradiation therapy for esophageal cancer in the elderly: clinical outcomes for patients exceeding 80 years old

C Xu, M Xi, A Moreno, Y Shiraishi, BP Hobbs… - International Journal of …, 2017 - Elsevier
Purpose The optimal treatment approach for patients≥ 80 years (“elderly”) with esophageal
cancer is not well established. We assessed the clinical outcomes in elderly patients treated …

A retrospective study of definitive chemoradiotherapy for elderly patients with esophageal cancer

S Takeuchi, A Ohtsu, T Doi, T Kojima… - American journal of …, 2007 - journals.lww.com
Objective: The efficacy and safety of definitive chemoradiotherapy (CRT) for elderly patients
with esophageal cancer have not been fully elucidated yet. We conducted a retrospective …

Toxicity and outcomes after chemoradiation for esophageal cancer in patients age 75 or older

RH Mak, HJ Mamon, DP Ryan… - Diseases of the …, 2010 - academic.oup.com
Randomized trials of chemoradiation for esophageal cancer have included very few patients
age≥ 75. In this retrospective study, we describe the outcomes and toxicity of full-dose …

A meta-analysis of concurrent chemoradiotherapy for advanced esophageal cancer

LL Zhu, L Yuan, H Wang, L Ye, GY Yao, C Liu… - PLoS …, 2015 - journals.plos.org
Background Concurrent chemoradiotherapy is a standard treatment for local advanced
esophageal cancer, but the outcomes are controversial. Our goals were to compare the …

Concurrent chemoradiotherapy with S-1 and cisplatin in advanced esophageal cancer

SH Cho, HJ Shim, SR Lee, JS Ahn… - Diseases of the …, 2008 - academic.oup.com
How best to manage advanced esophageal cancer remains unresolved, especially in
palliative care. Here, in a pilot study, we evaluated the efficacy and safety of concurrent …

Esophageal cancer treatment is underutilized among elderly patients in the USA

D Molena, M Stem, AL Blackford, AO Lidor - Journal of Gastrointestinal …, 2017 - Elsevier
Objectives Large numbers of elderly patients in the USA receive no treatment for
esophageal cancer, despite evidence that multimodality treatment can increase survival. Our …

Esophageal cancer: definitive chemoradiotherapy for elderly patients

R Wakui, H Yamashita, K Okuma… - Diseases of the …, 2010 - academic.oup.com
To investigate the efficacy and toxicity of definitive chemoradiotherapy (CRT) for elderly
patients with locally advanced esophageal cancer. Twenty-two patients aged over 75 that …

Exclusive chemoradiotherapy with or without radiation dose escalation in esophageal cancer: multicenter phase 2/3 randomized trial CONCORDE (PRODIGE-26)

G Crehange, C M'vondo, A Bertaut… - International Journal of …, 2021 - redjournal.org
Purpose/Objective (s) Increasing dose of chemoradiotherapy in locally advanced
esophageal cancer unsuitable for surgery has been a matter of debate in the last 2 decades …