Frequency and function of HIV-specific CD8+ T cells
SA Migueles, M Connors - Immunology letters, 2001 - Elsevier
The virus-specific CD8+ T cell responses of 27 HIV-infected patients were studied, including
a unique cohort of long term nonprogressors (LTNP) with normal CD4+ T cell counts, low …
a unique cohort of long term nonprogressors (LTNP) with normal CD4+ T cell counts, low …
Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors
JC Gea-Banacloche, SA Migueles… - The Journal of …, 2000 - journals.aai.org
The virus-specific CD8+ T cell responses of 21 HIV-infected patients were studied including
a unique cohort of long-term nonprogressors with low levels of plasma viral RNA and strong …
a unique cohort of long-term nonprogressors with low levels of plasma viral RNA and strong …
Impaired function of circulating HIV-specific CD8+ T cells in chronic human immunodeficiency virus infection
P Shankar, M Russo, B Harnisch… - Blood, The Journal …, 2000 - ashpublications.org
The functional status of circulating human immunodeficiency (HIV)-specific CD8 T cells in
chronically infected subjects was evaluated. By flow cytometry, only 5 of 7 subjects had …
chronically infected subjects was evaluated. By flow cytometry, only 5 of 7 subjects had …
Characterization of virus-specific CD8+ effector T cells in the course of HIV-1 infection: longitudinal analyses in slow and rapid progressors
CA Jansen, E Piriou, C Bronke, J Vingerhoed… - Clinical …, 2004 - Elsevier
Studies in humans have provided evidence that CD8+ T cells exhibit distinct phenotypical
and functional properties dependent on virus specificity. It is not known how these T-cell …
and functional properties dependent on virus specificity. It is not known how these T-cell …
Weak anti-HIV CD8+ T-cell effector activity in HIV primary infection
M Dalod, M Dupuis, JC Deschemin… - The Journal of …, 1999 - Am Soc Clin Investig
HIV-specific CD8+ T cells play a major role in the control of virus during HIV primary
infection (PI) but do not completely prevent viral replication. We used IFN-γ enzyme-linked …
infection (PI) but do not completely prevent viral replication. We used IFN-γ enzyme-linked …
HIV-specific cytotoxic cell frequencies measured directly ex vivo by the Lysispot assay can be higher or lower than the frequencies of IFN-γ-secreting cells: anti-HIV …
JE Snyder-Cappione, AA Divekar… - The Journal of …, 2006 - journals.aai.org
Abstract CD8+ T cells in HIV-infected patients are believed to contribute to the containment
of the virus and the delay of disease progression. However, the frequencies of HIV-specific …
of the virus and the delay of disease progression. However, the frequencies of HIV-specific …
Delayed Virus-Specific CD8+ Cytotoxic T Lymphocyte Activity in an HIV-Infected Individual with High CD4+ Cell Counts: Correlations with Various Parameters of …
M DALOD, S FIORENTINO, C DELAMARE… - AIDS research and …, 1996 - liebertpub.com
This 4-year longitudinal study monitored the temporal association between the HIV-specific
cytotoxic T lymphocyte (CTL) response and the control viremia in an individual infected with …
cytotoxic T lymphocyte (CTL) response and the control viremia in an individual infected with …
Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD4+ T Cells That Proliferate In Vitro Detected in Samples from Most Viremic Subjects and Inversely …
Diminished in vitro proliferation of human immunodeficiency virus type 1 (HIV-1)-specific
CD4+ T cells has been associated with HIV-1 viremia and declining CD4+ T-cell counts …
CD4+ T cells has been associated with HIV-1 viremia and declining CD4+ T-cell counts …
CD4 responses to conserved HIV-1 T helper epitopes show both negative and positive associations with virus load in chronically infected subjects
MJ Boaz, A Waters, S Murad… - Clinical & …, 2003 - academic.oup.com
Characterization of immune responses to immunodominant CD4 epitopes in HIV-1 that are
associated with control of HIV infection could be used to strengthen the efficacy of …
associated with control of HIV infection could be used to strengthen the efficacy of …
Expansion and contraction of HIV-specific CD4 T cells with short bursts of viremia, but physical loss of the majority of these cells with sustained viral replication
N Seth, D Kaufmann, T Lahey… - The Journal of …, 2005 - journals.aai.org
Chronic infection with the HIV results in poor HIV-specific CD4 T cell proliferation, but more
recent analyses using intracellular cytokine staining demonstrated that IFN-γ-producing, HIV …
recent analyses using intracellular cytokine staining demonstrated that IFN-γ-producing, HIV …