The Staphylococcus aureus allelic genetic loci for serotype 5 and 8 capsule expression contain the type-specific genes flanked by common genes

S Sau, N Bhasin, ER Wann, JC Lee… - …, 1997 - microbiologyresearch.org
The nucleotide sequences of two gene clusters, cap5 and cap8, involved in the synthesis of
Staphylococcus aureus type 5 and type 8 capsular polysaccharides (CPs), respectively …

Cloning of type 8 capsule genes and analysis of gene clusters for the production of different capsular polysaccharides in Staphylococcus aureus

S Sau, CY Lee - Journal of bacteriology, 1996 - Am Soc Microbiol
Eleven serotypes of capsular polysaccharide from Staphylococcus aureus have been
reported. We have previously cloned a cluster of type 1 capsule (cap1) genes responsible …

Genetic analysis of the cap5 locus of Staphylococcus aureus

ER Wann, B Dassy, JM Fournier… - FEMS microbiology …, 1999 - academic.oup.com
Staphylococcus aureus expresses at least eight distinct serotypes of capsular
polysaccharide (CP). Gene clusters involved in the expression of serotypes 1, 5 and 8 have …

Molecular characterization of the capsule locus from non‐typeable Staphylococcus aureus

JL Cocchiaro, MI Gomez, A Risley… - Molecular …, 2006 - Wiley Online Library
Most Staphylococcus aureus express a serotype 5 or 8 capsular polysaccharide (CP).
However, 20–25% of human isolates and up to 86% of bovine strains of S. aureus are non …

Cloning of genes affecting capsule expression in Staphylococcus aureus strain M

CY Lee - Molecular microbiology, 1992 - Wiley Online Library
Staphylococcus aureus strain M produces large amounts of capsular polysaccharide. It
produces a non‐encapsulated variant at a frequency of 0.01% at 37° C. At high temperature …

Molecular characterization and transcriptional analysis of type 8 capsule genes in Staphylococcus aureus

S Sau, J Sun, CY Lee - Journal of bacteriology, 1997 - Am Soc Microbiol
A 20.5-kb contiguous DNA fragment from Staphylococcus aureus Becker affecting type 8
capsule (CP8) biosynthesis was previously cloned. Sequencing analysis indicated that 16 …

Type 1 Capsule Genes of Staphylococcus aureus Are Carried in a Staphylococcal Cassette Chromosome Genetic Element

TT Luong, S Ouyang, K Bush, CY Lee - Journal of bacteriology, 2002 - Am Soc Microbiol
The cap1 genes are required for the synthesis of type 1 capsular polysaccharide (CP1) in
Staphylococcus aureus. We previously showed that the cap1 locus was associated with a …

Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus

WS Lin, T Cunneen, CY Lee - Journal of bacteriology, 1994 - Am Soc Microbiol
We previously cloned a 19.4-kb DNA region containing a cluster of genes affecting type 1
capsule production from Staphylococcus aureus M. Subcloning experiments showed that …

Promoter Analysis of the cap8 Operon, Involved in Type 8 Capsular Polysaccharide Production in Staphylococcus aureus

S Ouyang, S Sau, CY Lee - Journal of bacteriology, 1999 - Am Soc Microbiol
The production of type 8 capsular polysaccharide (CP8) in Staphylococcus aureus is
regulated in response to a variety of environmental factors. The cap8 genes required for the …

Overproduction of Type 8 Capsular Polysaccharide Augments Staphylococcus aureus Virulence

TT Luong, CY Lee - Infection and immunity, 2002 - Am Soc Microbiol
ABSTRACT Type 8 capsular polysaccharide (CP8) is the most prevalent capsule type in
clinical isolates of Staphylococcus aureus. However, its role in virulence has not been …