The majority of patients with chronic heart failure (HF) receive long-term treatment with loop
diuretics. The comparative effectiveness of different loop diuretics is unknown. We searched …

Background Loop diuretics are given to the majority of patients with chronic heart failure
(HF). Whether the different pharmacological properties of the three guideline-recommended …

Background Heart failure (HF) is a common condition associated with substantial cost,
morbidity, and mortality. Because results of clinical trials in the acute decompensated heart …

The focus of this review is to explore the controversy between the broad acceptance of loop
diuretics as a first-line treatment for heart failure (HF) and the data regarding their …

There is ongoing controversy regarding the association between loop diuretics (LD),
especially in high doses, and adverse clinical outcomes in outpatients with heart failure …

Although loop diuretics are the most commonly used drugs for the treatment of acute heart
failure (AHF), their short and long-term effects are relatively unknown. The use of loop …

Aims Loop diuretics have become a mainstay of chronic heart failure management.
Furosemide and torsemide are the two most common loop diuretics; nevertheless, there is …

Loop diuretics are recommended for relieving symptoms and signs of congestion in patients
with chronic heart failure and are administered to more than 80% of them. However, several …

Background Loop diuretics, when given as intermittent bolus injections in acutely
decompensated heart failure, may cause fluctuations in intravascular volume, increased …

Although approaches to optimize volume status, such as modifying fluid and salt intake, are
important, 1 use of loop diuretics remains the mainstay of treatment for congestion in …