An analysis of the composition of the inflammatory infiltrate in autoimmune and hepatitis B virus-induced chronic liver disease

L Montano, F Aranguibel, M Boffill, AH Goodall… - Hepatology, 1983 - journals.lww.com
The composition of the mononuclear cell infiltrate in the liver was studied in patients with
autoimmune and hepatitis B virus (HBV)-induced liver disease. The ratio of inducer to …

DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans.

ML Michel, HL Davis, M Schleef… - Proceedings of the …, 1995 - National Acad Sciences
Intramuscular injection of plasmid DNA expression vectors encoding the three envelope
proteins of the hepatitis B virus (HBV) induced humoral responses in C57BL/6 mice specific …

Intrahepatic distribution of hepatitis B surface and core antigens in chronic hepatitis B virus infection: hepatocyte with cytoplasmic/membranous hepatitis B core …

CM Chu, YF Liaw - Gastroenterology, 1987 - Elsevier
The intrahepatic distribution of hepatitis B core antigen (HbcAg) and surface antigen
(HBsAg) was studied in 32 patients with chronic type B hepatitis, and the results were …

DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice.

A Kuhöber, HP Pudollek, K Reifenberg… - … (Baltimore, Md.: 1950 …, 1996 - journals.aai.org
The serum Ab response and the class I-restricted CTL response of C57BL/6 (H-2b) mice to
hepatitis B (pre) core Ag (HBcAg, HBeAg) was studied. Injection of HBcAg particles without …

Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice.

A Franco, LG Guidotti, MV Hobbs… - … (Baltimore, Md.: 1950 …, 1997 - journals.aai.org
The pathogenetic effector functions of hepatitis B virus (HBV)-specific CD4+, Th1 cells were
analyzed in two inbred lineages of HBV transgenic mice, one of which overexpresses the …

Neutralization of hepatitis B virus infectivity by a murine monoclonal antibody: an experimental study in the chimpanzee

S Iwarson, E Tabor, HC Thomas… - Journal of Medical …, 1985 - Wiley Online Library
Two study chimpanzees were inoculated intravenously with approximately 1,000
chimpanzee infectious doses of hepatitis B virus (HBV), one with subtype adr and one with …

T cell subsets in patients with acute and chronic HBV infection, primary biliary cirrhosis and alcohol induced liver disease

HC Thomas - International Journal of Immunopharmacology, 1981 - Elsevier
The proportions of inducer and cytotoxic/suppressor T cells and their concentrations in
peripheral blood have been determined in patients with acute and chronic type B hepatitis …

In situ characterization by monoclonal antibodies of the mononuclear cell infiltrate in chronic active hepatitis

G Colucci, M Colombo, E Del Ninno, F Paronetto - Gastroenterology, 1983 - Elsevier
To characterize the inflammatory infiltrate of chronic active hepatitis we have examined 26
liver biopsy specimens [16 hepatitis B surface antigen-negative and 10 hepatitis B surface …

T and B lymphocytes in acute and chronic hepatitis

RJ DeHoratius, RG Strickland, RC Willams Jr - Clinical Immunology and …, 1974 - Elsevier
Peripheral blood thymus-dependent (TL) and bone marrow-dependent lymphocytes (BL)
were measured in healthy control subjects and patients with acute or chronic hepatitis with …

Incubation phase of acute hepatitis B in man: dynamic of cellular immune mechanisms

GJM Webster, S Reignat, MK Maini, SA Whalley… - Hepatology, 2000 - Elsevier
After hepatitis B virus (HBV) infection, liver injury and viral control have been thought to
result from lysis of infected hepatocytes by virus-specific cytotoxic T cells. Patients are …