Multiple treatment modalities for brain metastasis in patients with EGFR-mutant non-small-cell lung cancer

H Wang, X Yu, Y Fan, Y Jiang - OncoTargets and therapy, 2018 - Taylor & Francis
Background There are many controversies concerning the best management of epidermal
growth factor receptor (EGFR)-mutant non-small-cell lung cancer (NSCLC) patients with …

The optimal therapy strategy for epidermal growth factor receptor‐mutated non‐small cell lung cancer patients with brain metastasis: A real‐world study from Taiwan

WC Cheng, YC Shen, CR Chien, WC Liao… - Thoracic …, 2022 - Wiley Online Library
Background The treatment options for epidermal growth factor receptor (EGFR)‐mutated
non‐small cell lung cancer (NSCLC) with brain metastases (BMs) include EGFR‐tyrosine …

Combination of EGFR-Directed Tyrosine Kinase Inhibitors (EGFR-TKI) with Radiotherapy in Brain Metastases from Non-Small Cell Lung Cancer: A 2010-2019 …

S Saxena, A Khosla, A Ozair, R Kotecha… - …, 2023 - scholarlycommons.baptisthealth.net
Introduction: Traditionally, brain metastases have been treated with stereotactic radiosurgery
(SRS), whole-brain radiation (WBRT), and/or surgical resection. Non-small cell lung cancers …

Combination of EGFR-Directed Tyrosine Kinase Inhibitors (EGFR-TKI) with Radiotherapy in Brain Metastases from Non-Small Cell Lung Cancer: A 2010–2019 …

V Tatineni, PJ O'Shea, S Saxena, AA Khosla, A Ozair… - Cancers, 2023 - mdpi.com
Simple Summary Radiotherapy, in the form of either whole-brain radiotherapy (WBRT) or
stereotactic radiosurgery (SRS), continues as the standard of care for patients of non-small …

Paradigm shift of therapeutic management of brain metastases in EGFR-mutant non-small cell lung cancer in the era of targeted therapy

A Sekine, H Satoh - Medical Oncology, 2017 - Springer
Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR)
mutations commonly present brain metastases (BM) at the time of NSCLC diagnosis or …

Upfront cranial radiotherapy followed by erlotinib positively affects clinical outcomes of epidermal growth factor receptor-mutant non-small cell lung cancer with brain …

K Saruwatari, T Ikeda, S Saeki, N Shingu… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: The optimal treatment strategy for epidermal growth factor receptor (EGFR)-
mutant non-small cell lung cancer (NSCLC) patients with brain metastasis (BM) has not yet …

[HTML][HTML] EGFR-TKI plus brain radiotherapy versus EGFR-TKI alone in the management of EGFR-mutated NSCLC patients with brain metastases

K Dong, W Liang, S Zhao, M Guo, Q He… - Translational Lung …, 2019 - ncbi.nlm.nih.gov
Background It has been confirmed that epidermal growth factor receptor-tyrosine kinase
inhibitors (EGFR-TKIs) presented better efficacy than brain radiotherapy (brain RT) in the …

Management of brain metastases in tyrosine kinase inhibitor–naïve epidermal growth factor receptor–mutant non–small-cell lung cancer: a retrospective multi …

WJ Magnuson, NH Lester-Coll, AJ Wu… - Journal of clinical …, 2017 - ascopubs.org
Purpose Stereotactic radiosurgery (SRS), whole-brain radiotherapy (WBRT), and epidermal
growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are treatment options for …

Real‐world utilization of EGFR TKIs and prognostic factors for survival in EGFR‐mutated non‐small cell lung cancer patients with brain metastases

X Yu, J Sheng, G Pan, Y Fan - International Journal of Cancer, 2021 - Wiley Online Library
Brain metastases (BMs) cause morbidity and mortality in patients with non‐small cell lung
cancer (NSCLC). The optimal management of epidermal growth factor receptor (EGFR) …

Combined action of EGFR tyrosine kinase inhibitors and whole-brain radiotherapy on EGFR-mutated non-small-cell lung cancer patients with brain metastasis

Y Lu, Y Fan - OncoTargets and therapy, 2016 - Taylor & Francis
Background Lung cancer is the most common type of cancer to spread to the brain (brain
metastasis [BM]). This study assessed the effect of epidermal growth factor receptor (EGFR) …