Background Esophageal squamous cell carcinoma (ESCC) is one of the most frequent
malignancies in China and epidermal growth factor receptor (EGFR) is widely distributed in …

Alterations of the epidermal growth factor receptor (EGFR), including overexpression or
gene mutations, contribute to the malignant transformation of human epithelial cells. The aim …

Background In view of the prominent role in cancer cell biology and alteration in substantial
numbers of ESCC, defining EGFR molecular characteristics relevant to patient prognosis is …

Background: The molecular status of epidermal growth factor receptor (EGFR) in
esophageal cancer has not been well elucidated. The purpose of the study was to …

Esophageal squamous cell carcinoma (ESCC) exhibits abnormalities in epidermal growth
factor receptor (EGFR) gene. To identify a prognostic marker, the overexpression of EGFR …

Background: The epidermal growth factor receptor (EGFR) has become a promising target
for novel anticancer therapy. Evaluation of its biological profiles including gene mutation …

Overexpression of epidermal growth factor receptor (EGFR) is observed in many cancers,
sometimes accompanied by gene amplification. Recently, several clinical therapies …

Background Although epidermal growth factor receptor (EGFR) inhibitor treatment showed
modest response in several clinical trials in esophageal squamous cell carcinoma (ESCC) …

Background The overall survival of patients with esophageal squamous cell carcinoma
(ESCC) remains poor. Prognostic predictions in ESCC are usually based on histological …

The aim of the current study was to investigate the prognostic significance of epidermal
growth factor receptor (EGFR) in patients with locally advanced esophageal squamous cell …