Medical Treatment Options for Patients with Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer Suffering from Brain Metastases and …

M Hochmair - Targeted Oncology, 2018 - Springer
Brain metastases and/or leptomeningeal disease (LMD) with associated central nervous
system (CNS) metastases are known complications of advanced epidermal growth factor …

Preventing and treating brain metastases with three first-line EGFR-tyrosine kinase inhibitors in patients with EGFR mutation-positive advanced non-small cell lung …

PL Su, YL Wu, WY Chang, CL Ho… - Therapeutic …, 2018 - journals.sagepub.com
Introduction: Brain metastases (BM) are common in advanced non-small cell lung cancer
(NSCLC), and the prognosis is poor with few therapeutic options. This study evaluated the …

Different Tyrosine Kinase Inhibitors Used in Treating EGFR-Mutant Pulmonary Adenocarcinoma with Brain Metastasis and Intracranial Intervention Have No Impact on …

CY Kuo, MJ Tsai, JY Hung, KL Wu, YM Tsai, YC Tsai… - Cancers, 2022 - mdpi.com
Simple Summary Brain metastasis is a factor of a poor prognosis in patients with non-small-
cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations …

[HTML][HTML] Current progress and outcomes of clinical trials on using epidermal growth factor receptor-tyrosine kinase inhibitor therapy in non-small cell lung cancer …

LL Kong, LL Wang, LG Xing, JM Yu - Chronic Diseases and Translational …, 2017 - Elsevier
Non-small cell lung cancer (NSCLC) continues to be one of the major causes of cancer-
related deaths worldwide, and brain metastases are the major cause of death in NSCLC …

An active treatment of lung adenocarcinoma cancer with brain metastases: icotinib

Y Zhang, H Tang, J Li, M Li - OncoTargets and therapy, 2015 - Taylor & Francis
Lung cancer has the highest mortality rate of all cancers worldwide. A total of 70%–75% of
all lung cancers are non-small cell lung cancer (NSCLC) with two-thirds presenting with …

Impact of whole brain radiation therapy on CSF penetration ability of Icotinib in EGFR-mutated non-small cell lung cancer patients with brain metastases: Results of …

L Zhou, J He, W Xiong, Y Liu, J Xiang, Q Yu, M Liang… - Lung Cancer, 2016 - Elsevier
Objectives Whole-brain radiation therapy (WBRT) and epidermal growth factor receptor
tyrosine kinase inhibitors (EGFR-TKIs) are both treatment options for EGFR-mutated non …

Icotinib and whole-brain radiotherapy for the treatment in patients with brain metastases from EGFR-mutant nonsmall cell lung cancer: A retrospective study

AY Jiang, J Zhang, HL Luo, F Gao, YF Lv - Medicine, 2018 - journals.lww.com
Icotinib and whole-brain radiotherapy for the treatment in p... : Medicine Icotinib and whole-brain
radiotherapy for the treatment in patients with brain metastases from EGFR-mutant nonsmall …

Comparison of the efficacies of first-generation epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in patients with advanced non-small-cell …

N Aiko, T Shimokawa, K Miyazaki, Y Misumi, Y Agemi… - BMC cancer, 2018 - Springer
Background Compared with standard chemotherapy, epidermal growth factor receptor
tyrosine kinase inhibitors (EGFR-TKIs) are more effective in patients with advanced non …

Management of CNS metastases in patients with EGFR mutation-positive NSCLC

V Shetty, S Babu - Indian Journal of Cancer, 2019 - journals.lww.com
Central nervous system (CNS) metastases are a frequent and severe complication
associated with epidermal growth factor receptor (EGFR)-mutated non-small cell lung …

[HTML][HTML] Improving outcomes for brain metastases in EGFR mutated NSCLC

JW Carlisle, SS Ramalingam - Translational Lung Cancer …, 2019 - ncbi.nlm.nih.gov
© Translational lung cancer research. All rights reserved. Transl Lung Cancer Res 2019; 8
(Suppl 4): S355-S359| http://dx. doi. org/10.21037/tlcr. 2019.05. 08 by erlotinib, the median …