Human serum albumin (HSA) is an abundant plasma protein, which attracts great interest in
the pharmaceutical industry since it can bind a remarkable variety of drugs impacting their …

Spectrofluorometric, UV–vis spectroscopic and theoretical tools were recruited to
comprehend the interaction of acalabrutinib (ACP-196; ACLB) with human serum albumin …

The main mechanism for drug-drug interaction is displacement reaction of ligands from their
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …

Monitoring the interaction between drugs and proteins is critical to understanding drug
transport and metabolism underlying pharmacodynamics. The binding capacities to human …

Abstract Cefpirome (CFP), a fourth-generation cephalosporin for parenteral administration,
is highly influential against gram-negative and gram-positive bacteria. Multiple approaches …

The interaction between drugs and transport proteins, such as albumins, is a key factor in
drug bioavailability. One of the techniques commonly used for the evaluation of the drug …

Interaction behaviour of an anticancer drug, saracatinib (SCB) with human serum albumin
(HSA), the major carrier protein in human blood circulation was investigated using …

Introduction: Epidermal growth factor receptor (EGFR) expression is upregulated in many
tumors and its aberrant signaling drives progression of many cancer types. Consequently …

Apatinib mesylate (APM), a novel tyrosine kinase inhibitor, has been applied in treating
various cancers. In the present study, the binding mechanism of APM with bovine serum …

The fluorescence quenching of human serum albumin (HSA) by epinastine hydrochloride
(EPN) at pH 7.4 buffer was studied using absorption, fluorescence quenching, time …