Anidulafungin: a potent antifungal that targets Candida and Aspergillus

M Ghannoum, M D'Angelo - Infectious Diseases in Clinical …, 2005 - journals.lww.com
Anidulafungin (LY-303366, VER002) is a semisynthetic derivative of echinocandin B and a
potent antifungal agent active against a wide spectrum of fungal pathogens. We reviewed …

Anidulafungin: an echinocandin antifungal

MA Pfaller - Expert Opinion on Investigational Drugs, 2004 - Taylor & Francis
Anidulafungin (LY-303366, V-echinocandin™, Vicuron Pharmaceuticals, Inc.) is a new
echinocandin antifungal agent with broad spectrum activity against Candida and Aspergillus …

Anidulafungin: a new therapeutic approach in antifungal therapy. Pharmacology of anidulafungin.

M Catalan Gonzalez, JC Montejo Gonzalez - 2008 - cabidigitallibrary.org
Anidulafungin is a new echinocandin antifungal agent which inhibits β-1, 3-D-glucan
synthase and disrupts fungal cell-wall synthesis. It has marked antifungal activity against …

Anidulafungin: advantage for the newcomer?

MJ Rüping, JJ Vehreschild, F Farowski… - Expert Review of …, 2008 - Taylor & Francis
Anidulafungin is the most recently approved compound of the echinocandin antifungal class.
Its mode of action is the noncompetitive inhibition of β–(1, 3)-D-glucan synthesis. Potent …

Anidulafungin: review of a new echinocandin antifungal agent

RH Raasch - Expert review of anti-infective therapy, 2004 - Taylor & Francis
Anidulafungin (Vicuron Pharmaceuticals) is a new echinocandin antifungal with potent
activity against Aspergillus and Candida spp. Anidulafungin is a noncompetitive inhibitor of …

Anidulafungin: when and how? The clinician's view

J George, AC Reboli - Mycoses, 2012 - Wiley Online Library
Anidulafungin is the newest addition to the antifungal arsenal. It possesses fungicidal activity
against Candida spp., including isolates that are azole and polyene resistant. In addition, it …

Anidulafungin: a drug evaluation of a new echinocandin

JM Joseph, R Kim, AC Reboli - Expert Opinion on …, 2008 - Taylor & Francis
Background: Over the past two decades, the frequency and type of invasive fungal infections
have increased greatly and thus have driven the need for new antifungal agents …

Phase 2, randomized, dose-ranging study evaluating the safety and efficacy of anidulafungin in invasive candidiasis and candidemia

DS Krause, J Reinhardt, JA Vazquez… - Antimicrobial agents …, 2004 - Am Soc Microbiol
This study evaluated the safety and efficacy of anidulafungin, a novel echinocandin, in
patients with invasive candidiasis, including candidemia. A total of 123 eligible patients were …

Pharmacokinetics, antifungal activity and clinical efficacy of anidulafungin in the treatment of fungal infections

EL Kuti, JL Kuti - Expert opinion on drug metabolism & toxicology, 2010 - Taylor & Francis
Importance of the field: Anidulafungin is one of three available intravenous echinocandins
that plays an important role in the treatment of serious fungal infections. Currently …

Anidulafungin: a novel echinocandin

JA Vazquez, JD Sobel - Clinical infectious diseases, 2006 - academic.oup.com
Until recently, the treatment available for serious fungal infections was composed of
amphotericin B and azoles, and each class demonstrated significant limitations …