Clinical safety of inhaled corticosteroids for asthma in children: an update of long-term trials

S Pedersen - Drug safety, 2006 - Springer
Inhaled corticosteroids are established as the mainstay of maintenance therapy for chronic
asthma. However, there remains some debate regarding the safety of long-term use of these …

Effects of inhaled steroids on growth, bone metabolism and adrenal function

DB Allen - Expert review of respiratory medicine, 2007 - Taylor & Francis
Inhaled corticosteroids are a first-line therapy for persistent asthma in children. Major safety
concerns of long-term inhaled corticosteroid therapy include suppression of adrenal …

Long-term inhaled corticosteroids in preschool children at high risk for asthma

TW Guilbert, WJ Morgan, RS Zeiger… - … England Journal of …, 2006 - Mass Medical Soc
Background It is unknown whether inhaled corticosteroids can modify the subsequent
development of asthma in preschool children at high risk for asthma. Methods We randomly …

Inhaled corticosteroids and asthma control in children: assessing impairment and risk

G Rachelefsky - Pediatrics, 2009 - publications.aap.org
OBJECTIVE. To review the use of inhaled corticosteroids on asthma control in children by
using the new therapeutic paradigm outlined in the Expert Panel Report 3: Guidelines for the …

Inhaled corticosteroids in children: is there a 'safe'dosage?

AL Boner, GL Piacentini - Drug safety, 1993 - Springer
Inhaled corticosteroids are effective for the treatment of asthma. Because of the appreciation
of the importance of airway inflammation in the pathogenesis of the disease, these drugs are …

Inhaled corticosteroid therapy for asthma in preschool children: growth issues

DB Allen - Pediatrics, 2002 - publications.aap.org
Although inhaled corticosteroids (ICS) have emerged as the preventive treatment of choice
for persistent asthma, few studies have been conducted in infants and very young children …

Establishing a therapeutic index for the inhaled corticosteroids: Part II: Comparisons of systemic activity and safety among different inhaled corticosteroids

CA Sorkness - Journal of allergy and clinical immunology, 1998 - Elsevier
The systemic activity and safety of inhaled corticosteroids are best studied in randomized,
controlled, long-term trials with clinically relevant doses in subjects. These studies require …

Use of inhaled corticosteroids in pediatric asthma

H Bisgaard - Pediatric Pulmonology, 1997 - Wiley Online Library
Inhaled corticosteroids reduce asthma symptoms and exacerbations, improve lung function,
and reduce airway inflammation and bronchial hyperreactivity more effectively than other …

Safety of inhaled corticosteroids in children

DB Allen - Pediatric pulmonology, 2002 - Wiley Online Library
Inhaled corticosteroids (ICS) are now first‐line therapy for persistent asthma in children. The
major safety concerns of long‐term ICS therapy for childhood asthma are potential effects on …

Inhaled corticosteroids in childhood asthma: the story continues

WMC van Aalderen, AB Sprikkelman - European journal of pediatrics, 2011 - Springer
Inhaled corticosteroids (ICS) are the most effective anti-inflammatory drugs for the treatment
of persistent asthma in children. Treatment with ICS decreases asthma mortality and …