In radioiodine therapy for malignant thyroid disease, the pre-therapeutically administered
iodine-131-dose can reduce the potential of thyroid or thyroid carcinoma cells to absorb the …

Purpose Radioiodine-131 treatment has been a well-established therapy for benign thyroid
diseases for more than 75 years. However, the physiological reasons of the so-called …

First described by Rawson et al. in 1951, thyroid stunning has become a subject of
considerable controversy. Diagnostic whole body scan (DxWBS) images are usually …

Thyroid stunning is a radiobiological phenomenon. It may be defined as a temporary
suppression of iodine, trapping function of the thyrocytes and thyroid cancer cells as a result …

Thyroid stunning is usually defined as decreased uptake or trapping of radioiodine 131I by
normal thyroid tissue or differentiated thyroid cancer after diagnostic administration of 131I …

Aim: To understand stunning effects of a diagnostic dose of iodine-131 (1-131). Methods:
Four hundred and sixty-eight patients (101 males, 367 females, ages: 6-75 years) with well …

Background The origin of the reduction in thyroid uptake after a low activity iodine scan, so-
called stunning effect, is still controversial. Two explanations prevail: an individual cell …

Aim To review published in-vivo and in-vitro quantitative dosimetric studies on thyroid
stunning in order to derive novel data applicable in clinical practice. Methods A non-linear …

Radio-iodine therapy for thyroid carcinoma has been given for many years but its use
remains surrounded with controversies. Should patients routinely have thyroid remnants …

Recent clinical and experimental data demonstrate that thyroid stunning is caused by
previous irradiation and may influence the efficacy of 131I radiation therapy of thyroid cancer …