Mesenchymal stem cells as treatment for MS–progress to date

A Uccelli, A Laroni… - Multiple Sclerosis Journal, 2013 - journals.sagepub.com
The unmet need for therapies capable of repairing the central nervous system (CNS)
damage occurring in many diseases including multiple sclerosis (MS) has sparked the …

[HTML][HTML] The potential of mesenchymal stem cells for neural repair

RH Miller, L Bai, DP Lennon… - Discovery …, 2010 - discoverymedicine.com
Developing effective therapies for serious neurological insults remains a major challenge for
biomedical research. Despite intense efforts, the ability to promote functional recovery after …

Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseases

A Uccelli, A Laroni, MS Freedman - The Lancet Neurology, 2011 - thelancet.com
The rationale for use of adult stem cells as a treatment for neurological diseases such as
multiple sclerosis arose from the hope that they had the capacity to foster repair of the CNS …

Mesenchymal stem cells for neurological disorders

A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

Plasticity and therapeutic potential of mesenchymal stem cells in the nervous system

DG Phinney, I Isakova - Current pharmaceutical design, 2005 - ingentaconnect.com
Mesenchymal stem cells resident in adult bone marrow are best characterized by their
capacity to differentiate into connective tissue cell types such as adipocytes, chondrocytes …

[HTML][HTML] Progress of mesenchymal stem cell therapy for neural and retinal diseases

TK Ng, VR Fortino, D Pelaez… - World journal of stem …, 2014 - ncbi.nlm.nih.gov
Complex circuitry and limited regenerative power make central nervous system (CNS)
disorders the most challenging and difficult for functional repair. With elusive disease …

Concise review: mesenchymal stem cells in neurodegenerative diseases

R Volkman, D Offen - Stem cells, 2017 - academic.oup.com
Stem cell-based therapies for neurodegenerative diseases aim at halting clinical
deterioration by regeneration and by providing local support for damaged tissue …

Human mesenchymal stem cells in the treatment of neurological diseases

K Drela, P Siedlecka, A Sarnowska… - Acta Neurobiologiae …, 2013 - ane.pl
Here we provide a comprehensive data on the unique features of mesenchymal stem cells
(MSCs) which makes them feasible and preferred candidate for cell-based therapy in …

From the lab to patients: a systematic review and meta-analysis of mesenchymal stem cell therapy for stroke

MM Lalu, J Montroy, D Dowlatshahi, B Hutton… - Translational stroke …, 2020 - Springer
There may be the potential to improve stroke recovery with mesenchymal stem cells (MSCs);
however, questions about the efficacy and safety of this treatment remain. To address these …

[HTML][HTML] Mesenchymal stem cell therapy: a review of clinical trials for multiple sclerosis

A Alanazi, M Alassiri, D Jawdat, Y Almalik - Regenerative Therapy, 2022 - Elsevier
Multiple sclerosis (MS) is a disease of the central nervous system (CNS) that is the result of
the body's own immune cells being auto-reactive to the myelin regions of the body as if …