Mesenchymal stem cell therapy in stroke: a systematic review of literature in pre-clinical and clinical research

H Zheng, B Zhang, PY Chhatbar, Y Dong… - Cell …, 2018 - journals.sagepub.com
Exogenous stem cell therapy (SCT) has been recognized recently as a promising
neuroregenerative strategy to augment recovery in stroke survivors. Mesenchymal stem …

Functional role of mesenchymal stem cells in the treatment of chronic neurodegenerative diseases

D Lo Furno, G Mannino… - Journal of cellular …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) can differentiate into not only cells of mesodermal
lineages, but also into endodermal and ectodermal derived elements, including neurons …

CNS disease diminishes the therapeutic functionality of bone marrow mesenchymal stem cells

A Sargent, L Bai, G Shano, M Karl, E Garrison… - Experimental …, 2017 - Elsevier
Mesenchymal stem cells (MSCs) have emerged as a potentially powerful cellular therapy for
autoimmune diseases including multiple sclerosis (MS). Based on their success in treating …

Growing evidence supporting the use of mesenchymal stem cell therapies in multiple sclerosis: A systematic review

AG Oliveira, M Gonçalves, H Ferreira… - Multiple Sclerosis and …, 2020 - Elsevier
Background Multiple sclerosis (MS) typically arises in early/middle adulthood and is
characterized by a progressive disability of the central nervous system (CNS). Currently …

The role of mesenchymal stromal cells in spinal cord injury, regenerative medicine and possible clinical applications

S Forostyak, P Jendelova, E Sykova - Biochimie, 2013 - Elsevier
Diseases of the central nervous system still remain among the most challenging pathologies
known to mankind, having no or limited therapeutic possibilities and a very pessimistic …

Bone-marrow-derived mesenchymal stem cell therapy for neurodegenerative diseases

O Sadan, E Melamed, D Offen - Expert opinion on biological …, 2009 - Taylor & Francis
Background: Stem-cell-based therapy is a promising new approach to handling
neurodegenerative diseases. One of the most promising cellular sources is bone-marrow …

Mesenchymal stem cells: therapeutic outlook for stroke

O Honmou, R Onodera, M Sasaki, SG Waxman… - Trends in molecular …, 2012 - cell.com
Adult bone marrow-derived mesenchymal stem cells (MSCs) display a spectrum of
functional properties. Transplantation of these cells improves clinical outcome in models of …

Therapeutic applications of mesenchymal stem cells:: a comprehensive review

P Samadi, S Saki, H Manoochehri… - Current Stem Cell …, 2021 - ingentaconnect.com
Mesenchymal Stem Cells (MSCs) are one of the most promising tools for cell therapy, that
are isolated from bone marrow and many other adult tissues such as liver, cord blood …

Mesenchymal Stem Cell therapy in Ischemic stroke: a meta‐analysis of preclinical studies

D Sarmah, V Agrawal, P Rane, S Bhute… - Clinical …, 2018 - Wiley Online Library
Numerous preclinical studies have been carried out using mesenchymal stem cells (MSCs)
therapy for ischemic stroke. The purpose of the present meta‐analysis is to review the …

World-wide efficacy of bone marrow derived mesenchymal stromal cells in preclinical ischemic stroke models: systematic review and meta-analysis

N Satani, C Cai, K Giridhar, D McGhiey… - Frontiers in …, 2019 - frontiersin.org
Background: Following extensive, positive results in pre-clinical experiments, Bone Marrow
Derived-Mesenchymal Stromal Cells (BM-MSCs) are now being tested as a novel therapy …