Mesenchymal stem cells in drug/gene delivery: implications for cell therapy
SJ Greco, P Rameshwar - Therapeutic delivery, 2012 - Taylor & Francis
Stem cells have been therapeutically utilized in replacement of hematopoetic cells for
decades. This is in contrast to the recent emergence of adult stem cells as, perhaps, safe …
decades. This is in contrast to the recent emergence of adult stem cells as, perhaps, safe …
Neuroprotective features of mesenchymal stem cells
Bone marrow (BM) derived mesenchymal stem cells (MSC) differentiate into cells of the
mesodermal lineage but also, under certain experimental circumstances, into cells of the …
mesodermal lineage but also, under certain experimental circumstances, into cells of the …
Clinical experience with stem cells and other cell therapies in neurological diseases
D Karussis, P Petrou, I Kassis - Journal of the neurological sciences, 2013 - Elsevier
To overcome the limited capacity of the CNS for regeneration, the theoretical alternative
would be to use stem cells for more effective management of chronic degenerative and …
would be to use stem cells for more effective management of chronic degenerative and …
Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial
A Uccelli, A Laroni, R Ali, MA Battaglia… - The Lancet …, 2021 - thelancet.com
Summary Background Mesenchymal stem cells (MSCs), also known as mesenchymal
stromal cells, have been proposed as a promising therapeutic option for people with multiple …
stromal cells, have been proposed as a promising therapeutic option for people with multiple …
[图书][B] Mesenchymal stem cells: methods and protocols
DJ Prockop, DG Phinney, BA Bunnell - 2008 - Springer
For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied,
garnering much attention due to their broad therapeutic efficacy. In Mesenchymal Stem …
garnering much attention due to their broad therapeutic efficacy. In Mesenchymal Stem …
A focus on allogeneic mesenchymal stromal cells as a versatile therapeutic tool for treating multiple sclerosis
A Shokati, A Naser Moghadasi, M Nikbakht… - Stem Cell Research & …, 2021 - Springer
Multiple sclerosis (MS) is a central nervous system (CNS) chronic illness with autoimmune,
inflammatory, and neurodegenerative effects characterized by neurological disorder and …
inflammatory, and neurodegenerative effects characterized by neurological disorder and …
Cell-based therapies for stroke: promising solution or dead end? Mesenchymal stem cells and comorbidities in preclinical stroke research
F Laso-García, L Diekhorst… - Frontiers in …, 2019 - frontiersin.org
Stroke is a major health problem worldwide. It has been estimated that 90% of the
population attributable risk of stroke is due to risk factors such as aging, hypertension …
population attributable risk of stroke is due to risk factors such as aging, hypertension …
Cell therapy: the final frontier for treatment of neurological diseases
S Dutta, G Singh, S Sreejith, MK Mamidi… - CNS neuroscience & …, 2013 - Wiley Online Library
Neurodegenerative diseases are devastating because they cause increasing loss of
cognitive and physical functions and affect an estimated 1 billion individuals worldwide …
cognitive and physical functions and affect an estimated 1 billion individuals worldwide …
Clinical trials with mesenchymal stem cells: an update
T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
Safety and feasibility of repeated intrathecal allogeneic bone marrow‐derived mesenchymal stromal cells in patients with neurological diseases
K Pan, L Deng, P Chen, Q Peng, J Pan… - Stem cells …, 2019 - Wiley Online Library
Mesenchymal stromal cells (MSCs) have become the most commonly used adult stem cells
in regenerative medicine. Preclinical studies have shown that MSCs‐based therapy is a …
in regenerative medicine. Preclinical studies have shown that MSCs‐based therapy is a …