Metabolomics: basic principles and strategies

S Nalbantoglu - Molecular medicine, 2019 - books.google.com
Metabolomics is the study of metabolome within cells, biofluids, tissues, or organisms to
comprehensively identify and quantify all endogenous and exogenous low-molecular …

Metabolomics toward personalized medicine

M Jacob, AL Lopata, M Dasouki… - Mass spectrometry …, 2019 - Wiley Online Library
Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …

Mass spectrometry‐based metabolomics: applications to biomarker and metabolic pathway research

A Zhang, H Sun, G Yan, P Wang… - Biomedical …, 2016 - Wiley Online Library
Mass spectrometry‐based metabolomics has become increasingly popular in molecular
medicine. High‐definition mass spectrometry (MS), coupled with pattern recognition …

Modern analytical techniques in metabolomics analysis

A Zhang, H Sun, P Wang, Y Han, X Wang - Analyst, 2012 - pubs.rsc.org
Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …

Mass spectrometry-based metabolomics in translational research

SJ Kim, HE Song, HY Lee, HJ Yoo - Advanced Imaging and Bio …, 2021 - Springer
Metabolomics is the systematic study of metabolite profiles of complex biological systems,
and involves the systematic identification and quantification of metabolites. Metabolism is …

Challenges and emergent solutions for LC‐MS/MS based untargeted metabolomics in diseases

L Cui, H Lu, YH Lee - Mass spectrometry reviews, 2018 - Wiley Online Library
In the past decade, advances in liquid chromatography‐mass spectrometry (LC‐MS) have
revolutionized untargeted metabolomics analyses. By mining metabolomes more deeply …

Mass spectrometry-based metabolomics in health and medical science: A systematic review

X Zhang, Q Li, J Dou - RSC advances, 2020 - pubs.rsc.org
Metabolomics is the study of the investigation of small molecules derived from cellular and
organism metabolism, which reflects the outcomes of the complex network of biochemical …

Mass spectrometry-based cellular metabolomics: current approaches, applications, and future directions

TM Domenick, EL Gill, V Vedam-Mai… - Analytical …, 2020 - ACS Publications
(HRMS), has made it possible to generate metabolomics data sets comprising thousands of
molecular features, which can provide key insights into the biological phenomena …

Exploring disease through metabolomics

N Vinayavekhin, EA Homan… - ACS chemical biology, 2010 - ACS Publications
Metabolomics approaches provide an analysis of changing metabolite levels in biological
samples. In the past decade, technical advances have spurred the application of …

Advances in mass spectrometry-based multi-scale metabolomic methodologies and their applications in biological and clinical investigations

Z Wang, H Zhu, W Xiong - Science Bulletin, 2023 - Elsevier
Metabolomics is a nascent field of inquiry that emerged in the late 20 th century. It
encompasses the comprehensive profiling of metabolites across a spectrum of organisms …