The first‐dose pharmacokinetics of midazolam and its primary α‐hydroxy metabolite were
studied after single‐dose administration. Eligible study patients were enrolled into one of …

Background Midazolam, a benzodiazepine, is finding expanded use in neonatal intensive
care units. We studied the pharmacokinetics and metabolism of midazolam after a single …

In this study, the authors evaluate the pharmacodynamics, safety, and acceptability of a new
cherry‐flavored oral syrup formulation of midazolam. This randomized, double‐blind …

Twelve children 1-5 y old were randomly assigned to receive midazolam 0.2 mg. kg-1 either
by the intravenous (IV) or intranasal (IN) routes. After IN administration the rapid onset of …

Although midazolam is a frequently used sedative in neonatal intensive care units, its use in
preterm neonates has been off‐label. Recently, a new dosing advice for midazolam for …

We studied 30 children, aged 4 to 12 years, undergoing elective circumcision, premedicated
with midazolam 0.5 mg. kg− 1 and atropine 0.02 mg. kg− 1 by mouth. A modified postbox …

OBJECTIVE: To determine the steady-state plasma concentrations of midazolam in critically
ill infants and children. DESIGN: Prospective uncontrolled study conducted over 18 months …

Objective: To determine efficacy of midazolam as a sedative in mechanically ventilated
newborns. Design: Double blind randomized placebo controlled trial. Setting: Neonatal Unit …

A simple, selective high‐performance liquid chromatographic method with ultraviolet
detection at 220nm is described for quantitation of midazolam and its primary metabolite 1 …

In a randomized, double-blind, placebo-controlled study, the safety, efficacy and feasibility of
oral midazolam premedication in children were evaluated in an ambulatory surgery unit …