Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections
BACKGROUND & AIMS: The cytokine pattern secreted by T cells at the site of viral
replication may influence the final outcome of hepatitis B virus (HBV) and hepatitis C virus …
replication may influence the final outcome of hepatitis B virus (HBV) and hepatitis C virus …
Phenotypical analysis and cytokine release of liver‐infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiology
HF Löhr, JF Schlaak, G Gerken, B Fleischer, HP Dienes… - Liver, 1994 - Wiley Online Library
Cytokines released by infiltrating T cells may contribute to the hepatic injury in chronic
hepatitis. Therefore, we characterized peripheral blood‐and liver‐infiltrating T cells from …
hepatitis. Therefore, we characterized peripheral blood‐and liver‐infiltrating T cells from …
Predominant T-helper 1 cytokine profile of hepatitis B virus nucleocapsid-specific T cells in acute self-limited hepatitis B
A Penna, G Del Prete, A Cavalli, A Bertoletti… - Hepatology, 1997 - journals.lww.com
The cytokine pattern secreted by T cells on viral antigen recognition is believed to exert a
profound influence on both the type of disease caused by the infecting agent and the final …
profound influence on both the type of disease caused by the infecting agent and the final …
[PDF][PDF] Phenotypic and functional characterization of intrahepatic T lymphocytes during chronic hepatitis C
V Leroy, I Vigan, JF Mosnier, T Dufeu‐Duchesne… - …, 2003 - Wiley Online Library
The pathogenesis of liver cell injury during chronic hepatitis C (CHC) is poorly understood.
The cellular immune response is thought to play a key role in both inhibition of viral …
The cellular immune response is thought to play a key role in both inhibition of viral …
The role of intrahepatic immune effector cells in inflammatory liver injury and viral control during chronic hepatitis B infection
TJ Tang, J Kwekkeboom, JD Laman… - Journal of viral …, 2003 - Wiley Online Library
Cytotoxic T lymphocytes (CTL) and Kupffer cells play an important role in the immune control
of hepatitis B virus (HBV), but may also induce liver injury during infection. We investigated …
of hepatitis B virus (HBV), but may also induce liver injury during infection. We investigated …
Th1/Th2 cytokine profiles and their relationship to clinical features in patients with chronic hepatitis C virus infection
S Sobue, T Nomura, T Ishikawa, S Ito, K Saso… - Journal of …, 2001 - Springer
Purpose. An imbalance in helper T-cell type 1 (Th1) and type 2 (Th2) cytokines is suggested
to play an important role in the pathogenesis of chronic viral infections, but this issue is not …
to play an important role in the pathogenesis of chronic viral infections, but this issue is not …
Intrahepatic T cells in hepatitis B: viral control versus liver cell injury
B Rehermann - The Journal of experimental medicine, 2000 - rupress.org
Clearance of the hepatitis B virus (HBV), a noncytopathic double-stranded DNA virus,
requires the coordinated response of innate and adaptive, humoral and cellular immune …
requires the coordinated response of innate and adaptive, humoral and cellular immune …
Selective expansion of cytotoxic T lymphocytes with a CD4+ CD56+ surface phenotype and a T helper type 1 profile of cytokine secretion in the liver of patients …
V Barnaba, A Franco, M Paroli… - … (Baltimore, Md.: 1950 …, 1994 - journals.aai.org
Highly purified CD4+ T cells isolated from liver biopsies of patients with hepatitis B virus-
induced CAH had a strong cytotoxic activity and were comprised of a substantial number of …
induced CAH had a strong cytotoxic activity and were comprised of a substantial number of …
Cytokine patterns correlate with liver damage in patients with chronic hepatitis B and C
K Falasca, C Ucciferri, M Dalessandro… - Annals of Clinical & …, 2006 - Assoc Clin Scientists
T-cell immunoregulatory cytokines influence the persistence of hepatitis C virus (HCV)
chronic infection and the extent of liver damage. Th1 cytokines positively correlate with …
chronic infection and the extent of liver damage. Th1 cytokines positively correlate with …
Characterization of Liver T–Cell Receptor γδ+ T Cells Obtained From Individuals Chronically Infected With Hepatitis C Virus (Hcv): Evidence for These T Cells Playing …
CTK Tseng, E Miskovsky, M Houghton, GR Klimpel - Hepatology, 2001 - journals.lww.com
The pathogenic mechanisms involved in viral hepatitis are not completely understood.
Evidence suggests that the pathology associated with hepatitis C virus (HCV) and hepatitis …
Evidence suggests that the pathology associated with hepatitis C virus (HCV) and hepatitis …