[图书][B] DNA methylation: development, genetic disease and cancer
W Doerfler, P Böhm - 2006 - books.google.com
It has become apparent that the genomes of many organisms are characterized by unique
patterns of DNA methylation which can differ from genome segment to genome segment and …
patterns of DNA methylation which can differ from genome segment to genome segment and …
[图书][B] DNA methylation: molecular biology and biological significance
J Jost, H Saluz - 2013 - books.google.com
The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …
[HTML][HTML] New findings showing how DNA methylation influences diseases
F Sallustio, L Gesualdo, A Gallone - World Journal of Biological …, 2019 - ncbi.nlm.nih.gov
Abstract In 1975, Holliday and Pugh as well as Riggs independently hypothesized that DNA
methylation in eukaryotes could act as a hereditary regulation mechanism that influences …
methylation in eukaryotes could act as a hereditary regulation mechanism that influences …
DNA methylation and gene expression
H Cedar - DNA methylation: biochemistry and biological …, 1984 - Springer
Understanding the mechanisms involved in the regulation of gene expression in eukaryotic
organisms is one of the major challenges facing the modern molecular biologist. Despite …
organisms is one of the major challenges facing the modern molecular biologist. Despite …
DNA methylation in eukaryotic cells
A Razin, H Cedar - International review of cytology, 1984 - Elsevier
Publisher Summary This chapter discusses DNA methylation in eukaryotic cells. DNA
methylation pattern undergoes discrete changes, especially during the process of …
methylation pattern undergoes discrete changes, especially during the process of …
Mutagenic and epigenetic effects of DNA methylation
ML Gonzalgo, PA Jones - Mutation Research/Reviews in Mutation …, 1997 - Elsevier
Tumorigenesis begins with the disregulated growth of an abnormal cell that has acquired
the ability to divide more rapidly than its normal counterparts (Nowell, PC (1976) Science …
the ability to divide more rapidly than its normal counterparts (Nowell, PC (1976) Science …
Gene methylation patterns and expression
J Yisraeli, M Szyf - DNA methylation: biochemistry and biological …, 1984 - Springer
Three basic approaches have been employed in the study of the effect of DNA methylation
of particular genes on their expression. One approach uses chemicals that cause …
of particular genes on their expression. One approach uses chemicals that cause …
The role of DNA methylation in cancer genetics and epigenetics
PW Laird, R Jaenisch - Annual review of genetics, 1996 - annualreviews.org
▪ Abstract The past few years have seen a wider acceptance of a role for DNA methylation in
cancer. This can be attributed to three developments. First, the documentation of the over …
cancer. This can be attributed to three developments. First, the documentation of the over …
DNA methylation and cancer.
PA Jones - Cancer research, 1986 - europepmc.org
The main thrusts of the arguments that aberrant DNA methylation is involved in the
generation of tumor heterogeneity and progression can be summarized as follows. The …
generation of tumor heterogeneity and progression can be summarized as follows. The …
DNA methylation
RLP Adams - Principles of medical biology, 1996 - Elsevier
Methylation of DNA is a postreplicative modification and the study of DNA methylation
impinges on all areas of DNA metabolism. This is, not surprising as a modified base that …
impinges on all areas of DNA metabolism. This is, not surprising as a modified base that …