Antioxidant response element

AK Jaiswal - Biochemical pharmacology, 1994 - Elsevier
Antioxidant response element (ARE?), also referred to as electrophile response element
(EpRE), has been found in the promoter regions of rat and human NAD (P) H: quinone …

[HTML][HTML] ARE-and TRE-mediated Regulation of Gene Expression: RESPONSE TO XENOBIOTICS AND ANTIOXIDANTS (∗)

T Xie, M Belinsky, Y Xu, AK Jaiswal - Journal of Biological Chemistry, 1995 - ASBMB
Antioxidant response elements (AREs) containing 12-O-tetradecanoylphorbol-13-acetate
response element (TRE)(perfect AP1) and TRE-like (imperfect AP1) elements mediate high …

Electrophile and antioxidant regulation of enzymes that detoxify carcinogens.

T Prestera, P Talalay - … of the National Academy of Sciences, 1995 - National Acad Sciences
Detoxication (phase 2) enzymes, such as glutathione S-transferases (GSTs), NAD (P)
H:(quinone-acceptor) oxidoreductase (QR), and UDP-glucuronsyltransferase, are induced in …

Activation of antioxidant/electrophile-responsive elements in IMR-32 human neuroblastoma cells

JD Moehlenkamp, JA Johnson - Archives of biochemistry and biophysics, 1999 - Elsevier
The present investigation demonstrates distinct patterns of activation for antioxidant/
electrophile-responsive elements (ARE/EpREs) in cells of neuronal versus hepatic origin …

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

TH Rushmore, MR Morton, CB Pickett - Journal of Biological Chemistry, 1991 - Elsevier
We have characterized further the antioxidant responsive element (ARE) identified in the 5'-
flanking region of the rat glutathione S-transferase Ya subunit gene and the NAD (P) H …

Antioxidant-inducible genes

T Primiano, TR Sutter, TW Kensler - Advances in pharmacology, 1996 - Elsevier
Publisher Summary Antioxidants inhibit the propagation of free radical reactions. Because of
their widespread use as preservatives in processed foods, their biochemical effects have …

Caffeic Acid Phenethyl Ester Stimulates Human Antioxidant Response Element-mediated Expression of the NAD(P)H:Quinone Oxidoreductase (NQO1) Gene

AK Jaiswal, R Venugopal, J Mucha, AM Carothers… - Cancer research, 1997 - AACR
Caffeic acid phenethyl ester (CAPE) is a phenolic antioxidant derived from the propolis of
honeybee hives. CAPE was shown to inhibit the formation of intracellular hydrogen peroxide …

[HTML][HTML] Regulation of human NAD (P) H: quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element.

Y Li, AK Jaiswal - Journal of Biological Chemistry, 1992 - Elsevier
Deletion mutagenesis and transfection studies into hepatic (mouse hepatoma (Hepa-1) and
human hepatoblastoma (Hep-G2)) and nonhepatic (HeLa) cells indicated that high levels of …

Human Antioxidant‐Response‐Element‐Mediated Regulation of Type 1 NAD (P) H: quinone Oxidoreductase Gene Expression: Effect of Sulfhydryl Modifying Agents

Y Li, AK Jaiswal - European journal of biochemistry, 1994 - Wiley Online Library
Human antioxidant‐response element (hARE) containing two copies of the AP1/AP1‐like
elements arranged as inverse repeat is known to mediate basal and β‐naphthoflavone …

[HTML][HTML] Transcriptional regulation of the rat NAD (P) H: quinone reductase gene: identification of regulatory elements controlling basal level expression and inducible …

LV Favreau, CB Pickett - Journal of Biological Chemistry, 1991 - Elsevier
We have identified two regions in the 5'-flanking sequence of the rat quinone reductase
gene that contain xenobiotic responsive elements. The DNA sequence of the first region …