The efficacy and safety of inhaled fluticasone propionate/salmeterol and ipratropium/albuterol for the treatment of chronic obstructive pulmonary disease: an eight …

B Make, NA Hanania, R ZuWallack, C Kalberg… - Clinical …, 2005 - Elsevier
BACKGROUND:: The pathology of chronic obstructive pulmonary disease (COPD) includes
both obstructive and inflammatory components. OBJECTIVE:: The aim of this study was to …

Early onset of effect of salmeterol and fluticasone propionate in chronic obstructive pulmonary disease

J Vestbo, R Pauwels, JA Anderson, P Jones… - Thorax, 2005 - thorax.bmj.com
Background: Combined treatment with inhaled corticosteroids and long acting β2 agonists is
approved for the treatment of chronic obstructive pulmonary disease (COPD), but little is …

A short-term comparison of fluticasone propionate/salmeterol with ipratropium bromide/albuterol for the treatment of COPD

JF Donohue, C Kalberg, A Emmett, K Merchant… - … in Respiratory Medicine, 2004 - Springer
Background: This is the first comparison of two combination therapies, fluticasone
propionate/salmeterol and ipratropium bromide/albuterol (salbutamol), for the treatment of …

Salmeterol & Fluticasone 50 μg/250 μg bid in combination provides a better long-term control than salmeterol 50 μg bid alone and placebo in COPD patients already …

RW Dal Negro, C Pomari, S Tognella… - Pulmonary pharmacology …, 2003 - Elsevier
Bronchodilator agents are central to the symptomatic management of Chronic Obstructive
Pulmonary Disease (COPD), and long-acting inhaled bronchodilators are regarded as more …

Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial

TS Lapperre, JB Snoeck-Stroband… - Annals of internal …, 2009 - acpjournals.org
Background: Inhaled corticosteroids (ICSs) and long-acting β2-agonists (LABAs) are used to
treat moderate to severe chronic obstructive pulmonary disease (COPD). Objective: To …

Lung function and symptom improvement with fluticasone propionate/salmeterol and ipratropium bromide/albuterol in COPD: response by beta-agonist reversibility

ER Bleecker, A Emmett, G Crater, K Knobil… - Pulmonary pharmacology …, 2008 - Elsevier
This retrospective analysis of data from two multi-center, randomized, double-blind, parallel
group studies compared the efficacy of fluticasone propionate/salmeterol (FSC) 250/50mcg …

Fluticasone propionate/salmeterol for the treatment of chronic-obstructive pulmonary disease

MT Dransfield, WC Bailey - Expert Opinion on Pharmacotherapy, 2004 - Taylor & Francis
Chronic-obstructive pulmonary disease (COPD) is a global public health problem and its
impact is increasing. Although only smoking cessation has been shown to alter the natural …

[HTML][HTML] Predictive factors for evaluation of response to fluticasone propionate/salmeterol combination in severe COPD

AB Tonnel, I Tillie-Leblond, V Attali, Z Bavelele… - Respiratory …, 2011 - Elsevier
BACKGROUND: The predictive factors for treatment response in patients with severe
chronic obstructive pulmonary disease (COPD) are unknown. We investigated predictive …

Effect of fluticasone propionate/salmeterol (250/50) on COPD exacerbations and impact on patient outcomes

A Anzueto, GT Ferguson, G Feldman… - COPD: Journal of …, 2009 - Taylor & Francis
Prevention and treatment of COPD exacerbations are recognized as key goals in disease
management. This randomized, double-blind, parallel-group, multicenter study evaluated …

Controlled trial of inhaled fluticasone propionate in moderate to severe COPD

WH Thompson, P Carvalho, JP Souza, NB Charan - Lung, 2002 - Springer
Inhaled corticosteroids are often used in the treatment of stable chronic obstructive
pulmonary disease (COPD), however, studies of these agents have had mixed results …