Metabolomics in the clinic: A review of the shared and unique features of untargeted metabolomics for clinical research and clinical testing
AD Kennedy, BM Wittmann, AM Evans… - Journal of Mass …, 2018 - Wiley Online Library
Metabolomics is the untargeted measurement of the metabolome, which is composed of the
complement of small molecules detected in a biological sample. As such, metabolomic …
complement of small molecules detected in a biological sample. As such, metabolomic …
Metabolomics toward personalized medicine
M Jacob, AL Lopata, M Dasouki… - Mass spectrometry …, 2019 - Wiley Online Library
Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …
biomarker discovery and personalized medicine and has great potential to elucidate the …
Metabolomics: an emerging but powerful tool for precision medicine
CB Clish - Molecular Case Studies, 2015 - molecularcasestudies.cshlp.org
Metabolomics, which is defined as the comprehensive analysis of metabolites in a biological
specimen, is an emerging technology that holds promise to inform the practice of precision …
specimen, is an emerging technology that holds promise to inform the practice of precision …
Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision medicine
A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …
Metabolomics in clinical practice: improving diagnosis and informing management
JD Odom, VR Sutton - Clinical chemistry, 2021 - academic.oup.com
Background Metabolomics is the study of small molecules to simultaneously identify multiple
low molecular weight molecules in a system. Broadly speaking, metabolomics can be …
low molecular weight molecules in a system. Broadly speaking, metabolomics can be …
Mass spectrometry-based metabolomics for clinical study: Recent progresses and applications
In clinical study, metabolomics aims to characterize the metabolic disturbance at the disease
state using large cohorts and further provides diagnostic evidence at the small molecular …
state using large cohorts and further provides diagnostic evidence at the small molecular …
Metabolomics analysis for biomarker discovery: advances and challenges
MS Monteiro, M Carvalho, ML Bastos… - Current medicinal …, 2013 - ingentaconnect.com
Over the last decades there has been a change in biomedical research with the search for
single genes, transcripts, proteins, or metabolites being substituted by the coverage of the …
single genes, transcripts, proteins, or metabolites being substituted by the coverage of the …
Mass spectrometry-based metabolomics diagnostics–myth or reality?
OP Trifonova, DL Maslov, EE Balashova… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Metabolomics, one of the most high-promising technologies, is the most
recently developed post-genomics discipline for developing new diagnostic tests for future …
recently developed post-genomics discipline for developing new diagnostic tests for future …
Toward a standardized strategy of clinical metabolomics for the advancement of precision medicine
Despite the tremendous success, pitfalls have been observed in every step of a clinical
metabolomics workflow, which impedes the internal validity of the study. Furthermore, the …
metabolomics workflow, which impedes the internal validity of the study. Furthermore, the …
[HTML][HTML] Progress in metabolomics standardisation and its significance in future clinical laboratory medicine
DA Dias, T Koal - Ejifcc, 2016 - ncbi.nlm.nih.gov
Today, the technology of 'targeted'based metabolomics is pivotal in the clinical analysis
workflow as it provides information of metabolic phenotyping (metabotypes) by enhancing …
workflow as it provides information of metabolic phenotyping (metabotypes) by enhancing …