Mass spectrometry-based metabolomics in health and medical science: A systematic review

X Zhang, Q Li, J Dou - RSC advances, 2020 - pubs.rsc.org
Metabolomics is the study of the investigation of small molecules derived from cellular and
organism metabolism, which reflects the outcomes of the complex network of biochemical …

Metabolomics biotechnology, applications, and future trends: a systematic review

Q Yang, A Zhang, J Miao, H Sun, Y Han, G Yan, F Wu… - RSC …, 2019 - pubs.rsc.org
Given the highly increased incidence of human diseases, a better understanding of the
related mechanisms regarding endogenous metabolism is urgently needed. Mass …

Mass spectrometry-based metabolomics for clinical study: Recent progresses and applications

J Ding, YQ Feng - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
In clinical study, metabolomics aims to characterize the metabolic disturbance at the disease
state using large cohorts and further provides diagnostic evidence at the small molecular …

Metabolomics: basic principles and strategies

S Nalbantoglu - Molecular medicine, 2019 - books.google.com
Metabolomics is the study of metabolome within cells, biofluids, tissues, or organisms to
comprehensively identify and quantify all endogenous and exogenous low-molecular …

Mass spectrometry‐based metabolomics: applications to biomarker and metabolic pathway research

A Zhang, H Sun, G Yan, P Wang… - Biomedical …, 2016 - Wiley Online Library
Mass spectrometry‐based metabolomics has become increasingly popular in molecular
medicine. High‐definition mass spectrometry (MS), coupled with pattern recognition …

Current state of the art of mass spectrometry-based metabolomics studies–a review focusing on wide coverage, high throughput and easy identification

Y Wang, S Liu, Y Hu, P Li, JB Wan - Rsc Advances, 2015 - pubs.rsc.org
Metabolomics aims at the comprehensive assessment of a wide range of endogenous
metabolites and attempts to identify and quantify the attractive metabolites in a given …

Metabolomics: small molecules that matter more

BC Muthubharathi, T Gowripriya, K Balamurugan - Molecular omics, 2021 - pubs.rsc.org
Metabolomics, an analytical study with high-throughput profiling, helps to understand
interactions within a biological system. Small molecules, called metabolites or metabolomes …

Advances in mass spectrometry-based metabolomics for investigation of metabolites

JL Ren, AH Zhang, L Kong, XJ Wang - RSC advances, 2018 - pubs.rsc.org
Metabolomics is the systematic study of all the metabolites present within a biological
system, which consists of a mass of molecules, having a variety of physical and chemical …

Metabolomics analysis for biomarker discovery: advances and challenges

MS Monteiro, M Carvalho, ML Bastos… - Current medicinal …, 2013 - ingentaconnect.com
Over the last decades there has been a change in biomedical research with the search for
single genes, transcripts, proteins, or metabolites being substituted by the coverage of the …

Toward a standardized strategy of clinical metabolomics for the advancement of precision medicine

NP Long, TD Nghi, YP Kang, NH Anh, HM Kim… - Metabolites, 2020 - mdpi.com
Despite the tremendous success, pitfalls have been observed in every step of a clinical
metabolomics workflow, which impedes the internal validity of the study. Furthermore, the …