Simple Summary Advancements in thyroid cancer are dependent on the availability of
experimental models allowing for investigation in the laboratory setting. Here, we detail the …

The overall prognosis of thyroid cancer is excellent, but some patients have grossly invasive
disease and distant metastases with limited responses to systemic therapies. Thus, relevant …

A significant number of well-differentiated thyroid cancers progress or recur, becoming
resistant to current therapeutic options. Mouse models recapitulating the genetic and …

Background: Tumor-derived cell lines are widely used to study the mechanisms involved in
thyroid carcinogenesis but recent studies have reported redundancy among thyroid cancer …

Starting from different regional samples taken from a heterogeneous follicular thyroid cancer
recurrence in a male patient, a series of cell cultures was initiated. Three stable cancer cell …

Thyroid cancer is the most common endocrine neoplasm, and its rate is rising at an alarming
pace. Thus, there is a compelling need to develop in vivo models which will not only enable …

Thyroid carcinomas, the most common endocrine tumors in humans, have an increasing
incidence in the US and worldwide. There are four major types of thyroid cancers: papillary …

Thyroid carcinomas are the most common endocrine neoplasms in humans, with a globally
increasing incidence. Thyroid follicular cells and neuroendocrine (parafollicular) C cells are …

Our understanding of the molecular mechanisms responsible for follicular thyroid cell
oncogenesis has been advanced significantly in recent years. Specific genetic alterations …

Background: Poorly differentiated and anaplastic thyroid carcinomas have a rather poor
prognosis. The development of relevant model systems to unravel in vitro and in vivo the …