Development of novel follicular thyroid cancer models which progress to poorly differentiated and anaplastic thyroid cancer
CO Caperton, LA Jolly, N Massoll, AJ Bauer, AT Franco - Cancers, 2021 - mdpi.com
Simple Summary Advancements in thyroid cancer are dependent on the availability of
experimental models allowing for investigation in the laboratory setting. Here, we detail the …
experimental models allowing for investigation in the laboratory setting. Here, we detail the …
[HTML][HTML] Preclinical models of follicular cell-derived thyroid cancer: an overview from cancer cell lines to mouse models
MJ Jeon, BR Haugen - Endocrinology and Metabolism, 2022 - synapse.koreamed.org
The overall prognosis of thyroid cancer is excellent, but some patients have grossly invasive
disease and distant metastases with limited responses to systemic therapies. Thus, relevant …
disease and distant metastases with limited responses to systemic therapies. Thus, relevant …
Mouse models of follicular and papillary thyroid cancer progression
MA Russo, VGA Arciuch, A Di Cristofano - Frontiers in Endocrinology, 2012 - frontiersin.org
A significant number of well-differentiated thyroid cancers progress or recur, becoming
resistant to current therapeutic options. Mouse models recapitulating the genetic and …
resistant to current therapeutic options. Mouse models recapitulating the genetic and …
Potential utility and limitations of thyroid cancer cell lines as models for studying thyroid cancer
T Pilli, KV Prasad, S Jayarama, F Pacini, BS Prabhakar - Thyroid, 2009 - liebertpub.com
Background: Tumor-derived cell lines are widely used to study the mechanisms involved in
thyroid carcinogenesis but recent studies have reported redundancy among thyroid cancer …
thyroid carcinogenesis but recent studies have reported redundancy among thyroid cancer …
Clonally related but phenotypically divergent human cancer cell lines derived from a single follicular thyroid cancer recurrence (TT2609)
AA Geldof, RT Versteegh, JC van Mourik… - Thyroid, 2001 - liebertpub.com
Starting from different regional samples taken from a heterogeneous follicular thyroid cancer
recurrence in a male patient, a series of cell cultures was initiated. Three stable cancer cell …
recurrence in a male patient, a series of cell cultures was initiated. Three stable cancer cell …
Mouse models of thyroid cancer: A 2015 update
Thyroid cancer is the most common endocrine neoplasm, and its rate is rising at an alarming
pace. Thus, there is a compelling need to develop in vivo models which will not only enable …
pace. Thus, there is a compelling need to develop in vivo models which will not only enable …
Modeling thyroid cancer in the mouse
XG Zhu, SY Cheng - Hormone and metabolic research, 2009 - thieme-connect.com
Thyroid carcinomas, the most common endocrine tumors in humans, have an increasing
incidence in the US and worldwide. There are four major types of thyroid cancers: papillary …
incidence in the US and worldwide. There are four major types of thyroid cancers: papillary …
Genetic alterations in thyroid cancer: the role of mouse models
KAB Knostman, SM Jhiang… - Veterinary pathology, 2007 - journals.sagepub.com
Thyroid carcinomas are the most common endocrine neoplasms in humans, with a globally
increasing incidence. Thyroid follicular cells and neuroendocrine (parafollicular) C cells are …
increasing incidence. Thyroid follicular cells and neuroendocrine (parafollicular) C cells are …
Well differentiated follicular thyroid neoplasia: impact of molecular and technological advances on detection, monitoring and treatment
AG Gianoukakis, SM Giannelli, WA Salameh… - Molecular and cellular …, 2011 - Elsevier
Our understanding of the molecular mechanisms responsible for follicular thyroid cell
oncogenesis has been advanced significantly in recent years. Specific genetic alterations …
oncogenesis has been advanced significantly in recent years. Specific genetic alterations …
Establishment and characterization of cell lines from a novel mouse model of poorly differentiated thyroid carcinoma: powerful tools for basic and preclinical research
M Dima, KA Miller, VG Antico-Arciuch, A Di Cristofano - Thyroid, 2011 - liebertpub.com
Background: Poorly differentiated and anaplastic thyroid carcinomas have a rather poor
prognosis. The development of relevant model systems to unravel in vitro and in vivo the …
prognosis. The development of relevant model systems to unravel in vitro and in vivo the …
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