Studies using high dose testosterone (T) administration in normal men as a male
contraceptive have resulted in azoospermia rates of only 50-70%. Previous studies of T and …

Monthly injections of testosterone undecanoate (TU) act as a male contraceptive by
reversibly suppressing spermatogenesis to azoospermia or severe oligoazoospermia in …

Hormonal suppression of spermatogenesis is currently being investigated as a method of
reversible male contraception. However, administration of exogenous testosterone (T) …

The development of a safe, well‐tolerated, effective, and reversible male hormonal
contraceptive would be a major clinical advance for couples planning their family size and …

Studies using exogenous high‐dosage testosterone (T) or a combination regimen of
physiologic T plus high‐dosage levonorgestrel (LNG) administration in normal men have …

In male contraceptive trials, approximately half of normal men become azoospermic on high
dosages of testosterone enanthate (TE), whereas the other half of men become severely …

Research has established the principle of hormonal male contraception based on
suppression of gonadotropins and spermatogenesis. All hormonal male contraceptives use …

In normal men, chronic testosterone (T) administration results in negative feedback
suppression of gonadotropin and sperm production. However, azoospermia is achieved in …

BACKGROUND: Combined testosterone and progestogen preparations are a promising
approach to male hormonal contraception. We investigated the effect of sc etonogestrel with …

Sex-steroid based male contraceptive regimes induce azoospermia in only 40-70% of
Caucasian men. The reason (s) why the remainder maintains a low level of …