Objective Acute hypoxia causes vasoconstriction in the pulmonary arteries. This hypoxic
pulmonary vasoconstriction (HPV) has been reported to be common in subjects exposed to …

In pulmonary hypertension right ventricular pressure overload leads to abnormal left
ventricular (LV) diastolic function. Acute high-altitude exposure is associated with hypoxia …

Smith TG, Talbot NP, Chang RW, Wilkinson E, Nickol AH, Newman DG, Robbins PA,
Dorrington KL. Pulmonary artery pressure increases during commercial air travel in healthy …

Exaggerated hypoxia-induced pulmonary hypertension is a hallmark of high-altitude
pulmonary edema (HAPE) and plays a major role in its pathogenesis. Many studies of HAPE …

Abstract Luks, Andrew M. Can patients with pulmonary hypertension travel to high altitude?
High Alt. Med. Biol. 10: 215–219, 2009.—With the increasing popularity of adventure travel …

To verify the abnormal pulmonary vascular response implicated in the pathogenesis of high
altitude pulmonary edema (HAPE), we examined the hemodynamic responses to hypoxia in …

More than 140 million people are living at high altitude worldwide. An increase of pulmonary
artery pressure (PAP) is a hallmark of high-altitude exposure and, if pronounced, may be …

Chronic hypoxia-induced sustained pulmonary vasoconstriction and vascular remodeling
lead to mild-to-moderate elevation of pulmonary artery pressure in high-altitude residents …

Abstract Baggish, Aaron L., Charles S. Fulco, Stephen Muza, Paul B. Rock, Beth Beidleman,
Allen Cymerman, Kibar Yared, Peter Fagenholz, David Systrom, Malissa J. Wood, Arthur E …

Abstract Dehnert, Christoph, Derliz Mereles, Sebastian Greiner, Dagmar Albers, Fabian
Scheurlen, Stefanie Zügel, Thomas Böhm, Peter Vock, Marco Maggiorini, Ekkehard Grünig …