Histological changes following epidural injection of midazolam in the neonatal rabbit

P Bozkurt, Y TUNALI, G KAYA, I OKAR - Pediatric Anesthesia, 1997 - Wiley Online Library
Midazolam can produce antinociceptive effects when used via intrathecal or epidural routes.
Neurotoxicity studies are scanty especially for neonates. The aim of this study was to carry …

Acute phase histopathological study of spinally administered midazolam in cats

T Nishiyama, T Matsukawa, K Hanaoka - Anesthesia & Analgesia, 1999 - journals.lww.com
Midazolam may be a useful analgesic when administered intrathecally. However,
neurotoxicity must be excluded. The purpose of this study was to investigate whether …

Midazolam in paediatric anaesthesia

WHJ Cole - Anaesthesia and intensive care, 1982 - journals.sagepub.com
Midazolam was given intravenously to 100 children over the age of 8 years to induce
anaesthesia and a similar control group was anaesthetised with diazepam. The actions of …

Resedation after bolus administration of midazolam to an infant and its reversal by flumazenil

S Collins, JA Carter - Anaesthesia, 1991 - Wiley Online Library
Resedation after bolus administration of midazolam to an infant and its reversal by
flumazenil Page 1 Anaesthesia, 1991, Volume 46, pages 471-472 CASE REPORT …

Neurotoxicity with single dose intrathecal midazolam administration

B Ugur, K Basaloglu, T Yurtseven, U Ates… - European journal of …, 2005 - cambridge.org
SummaryBackground and objective: The aim of study was to investigate the electron
microscopic changes in the medulla of the spinal cord that occur with intrathecal midazolam …

Injectable midazolam as oral premedicant in pediatric neurosurgery

LD Mishra, GK Sinha, PB Rao, V Sharma… - Journal of …, 2005 - journals.lww.com
In a randomized, double blind, placebo controlled study; the acceptability, efficacy and
safety of injectable midazolam as oral premedicant in children was evaluated. One hundred …

Midazolam potentiates nociceptive behavior, sensitizes cutaneous reflexes, and is devoid of sedative action in neonatal rats

SC Koch, M Fitzgerald, GJ Hathway - The Journal of the American …, 2008 - pubs.asahq.org
Background The significant postnatal maturation of gamma-aminobutyric acid signaling in
the developing brain is likely to have important implications for infant pain processing …

A new route, jet injection for anesthetic induction in children. IV. Midazolam plasma levels.

EF Domino, EK Zsigmoid, V Kovacs… - … journal of clinical …, 1998 - europepmc.org
The jet injector route for midazolam was used in 40 children 1-6 years of age undergoing
various short duration surgical procedures. A randomly selected dose of 100, 150, and 200 …

Midazolam versus atropine plus pethidine as premedication in children

S Sjövall, J Kanto, E Iisalo, JJ Himberg… - Anaesthesia, 1984 - Wiley Online Library
The effects of oral midazolam or intramuscular atropine and pethidine used as
premedication in two groups of 35 children over 5 years of age were studied. There was …

Plasma concentrations of midazolam after iv, nasal or rectal administration in children

JM Malinovsky, C Lejus, F Servin… - BJA: British Journal …, 1993 - academic.oup.com
Midazolam is used frequently for premedication in children, preferably by non-parenteral
administration. We have compared plasma concentrations of midazolam after nasal, rectal …