A versatile, computationally efficient two-dimensional (2D) speckle-tracking method based
on high resolution ultrasound imaging is proposed to quantify regional myocardial …

The study of transgenic mouse models of human cardiovascular disease has been limited
by the small size and high heart rate of the mouse heart. Advances in digital …

BACKGROUND: The accurate assessment of cardiac function in mice is challenging
because of their small heart size and rapid heart rate. METHODS: We examined the …

Ventricular remodeling, decreased left ventricular systolic function, and heart failure have
been associated with poor long-term outcomes after myocardial infarction [1, 2]. Thus, it is …

The severity of left ventricular (LV) dysfunction in rats with myocardial infarction (MI) varies
widely. Because homogeneity in baseline parameters is essential for experimental …

Regional left ventricular (LV) dysfunction induced by ischemia/infarction is accompanied by
increased end-systolic stress because the ischemic LV wall is unable to generate enough …

BACKGROUND: Mice are now widely used as models of cardiovascular disease. Their
small size and fast heart rates are technically challenging to echocardiography. This study …

Results: At initial presentation, 2-chamber longitudinal strain (9.4±3.5% vs.–11.6±3.6%, p<
0.04) and 4-chamber transverse strain (10.4±8.2% vs. 15.6±8%, p< 0.003) were lower in the …

Background: New echocardiographic contrast agents are commonly tested in the dog
model. However, this species has a number of drawbacks, including difficulties in …

BACKGROUND: We investigated whether the extent of residual myocardial viability
demonstrated by myocardial contrast echocardiography (MCE) predicts the degree of left …