Tumor Antigen Carcinoembryonic Antigen Inhibits Human CD4 Helper T Cell Activation

송유찬 - 2012 - s-space.snu.ac.kr
Carcinoembryonic antigen (CEA) is a well-known tumor antigen. It is found in serum of
various cancers including colorectal carcinoma, gastric carcinoma. Uncontrolled level of …

Carcinoembryonic antigen signaling suppresses the activation of human T cells by a SHP-independent mechanism: a potential mechanism for tumor-mediated …

E Bae, KA Lee, YC Song, CY Kang - The Journal of Immunology, 2015 - journals.aai.org
Carcinoembryonic antigen (CEA) is a well-known tumor antigen that is found in the serum of
patients with various cancers and is correlated with an increased risk of cancer recurrence …

A multimeric carcinoembryonic antigen signal inhibits the activation of human T cells by a SHP‐independent mechanism: A potential mechanism for tumor‐mediated …

KA Lee, EA Bae, YC Song, EK Kim… - … journal of cancer, 2015 - Wiley Online Library
Carcinoembryonic antigen (CEA) is a well‐known tumor antigen that is found in the serum of
patients with various cancers and is correlated with an increased risk of cancer recurrence …

The carcinoembryonic antigen (CEA) modulates effector‐target cell interaction by binding to activated lymphocytes

R Kammerer, S von Kleist - International journal of cancer, 1996 - Wiley Online Library
We and others have shown that the carcinoembryonic antigen (CEA) modulates the
susceptibility of human colorectal carcinoma cells to cytotoxic lymphocytes. We now …

Dendritic cells pulsed with CEA peptide induce CEA-specific CTL with restricted TCR repertoire

SE Alters, JR Gadea, M Sorich… - Journal of …, 1998 - journals.lww.com
The human carcinoembryonic antigen (CEA), which is expressed in several cancer types is
a potential target for antigen-specific immunotherapy. In this study, we show that dendritic …

[PDF][PDF] Carcinoembryonic Antigen-Related Cellular

I Alternatively - J Immunol, 2004 - academia.edu
Carcinoembryonic Ag-related cellular adhesion molecule 1 (CEACAM1) represents a group
of transmembrane protein isoforms that consist of variable numbers of extracellular Ig-like …

Abstract B120: Characterization and combination immunotherapy treatment of an inducible autochthonous murine lung cancer model expressing human …

EF Zhu, K Rakhra, N Mehta, KD Moynihan… - Cancer Immunology …, 2016 - AACR
Previous work from our lab has demonstrated that a combination of anti-tumor antibody and
an IL-2 fusion protein that exhibits extended serum half-life elicits an immune response that …

CEACAMI as a negative regulator of T cell functions

J Farrah - 2003 - escholarship.mcgill.ca
CEA-related cell adhesion molecule 1 (CEACAMl) is a member of the carcinoembryonic
antigen (CEA) family that is expressed on activated T lymphocytes. Previous studies have …

Induction of CEA-specific Cytotoxic T Lymphocytes by Murine Dendritic Cells Expressing CEA

EH Won, CH Kim, MY Park, HI Cho, ST Oh… - Immune …, 2003 - koreascience.kr
Background: Carcinoembryonic antigen (CEA) is well-known soluble tumor marker
frequently detectable in peripheral blood of carcinoma patients and considered as good …

Characterization of genetically modified T-cell receptors that recognize the CEA: 691-699 peptide in the context of HLA-A2. 1 on human colorectal cancer cells

MR Parkhurst, J Joo, JP Riley, Z Yu, Y Li… - Clinical Cancer …, 2009 - AACR
Purpose: Carcinoembryonic antigen (CEA) is a tumor-associated protein expressed on a
variety of adenocarcinomas. To develop an immunotherapy for patients with cancers that …