Termination of transcription of short noncoding RNAs by RNA polymerase II
The RNA polymerase II transcription cycle is often divided into three major stages: initiation,
elongation, and termination. Research over the last decade has blurred these divisions and …
elongation, and termination. Research over the last decade has blurred these divisions and …
Transcription termination and the control of the transcriptome: why, where and how to stop
O Porrua, D Libri - Nature reviews Molecular cell biology, 2015 - nature.com
Transcription termination occurs when the polymerase is released after a transcription event,
thus delimitating transcription units; however, the functional importance of termination …
thus delimitating transcription units; however, the functional importance of termination …
Overlapping pathways dictate termination of RNA polymerase II transcription
S Lykke-Andersen, TH Jensen - Biochimie, 2007 - Elsevier
While it has long been appreciated that regulation of transcription initiation is vital to sustain
dynamic gene expression, recent findings suggest that the control of transcription …
dynamic gene expression, recent findings suggest that the control of transcription …
[HTML][HTML] Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast
HE Mischo, NJ Proudfoot - Biochimica et Biophysica Acta (BBA)-Gene …, 2013 - Elsevier
Termination of transcription by RNA polymerase II requires two distinct processes: The
formation of a defined 3′ end of the transcribed RNA, as well as the disengagement of RNA …
formation of a defined 3′ end of the transcribed RNA, as well as the disengagement of RNA …
Unravelling the means to an end: RNA polymerase II transcription termination
JN Kuehner, EL Pearson, C Moore - Nature reviews Molecular cell …, 2011 - nature.com
The pervasiveness of RNA synthesis in eukaryotes is largely the result of RNA polymerase II
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …
The Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain
Abstract RNA polymerase II (Pol II) in Saccharomyces cerevisiae can terminate transcription
via several pathways. To study how a mechanism is chosen, we analyzed recruitment of …
via several pathways. To study how a mechanism is chosen, we analyzed recruitment of …
[HTML][HTML] RNA polymerase II CTD tyrosine 1 is required for efficient termination by the Nrd1-Nab3-Sen1 pathway
In Saccharomyces cerevisiae, transcription termination at protein-coding genes is coupled to
the cleavage of the nascent transcript, whereas most non-coding RNA transcription relies on …
the cleavage of the nascent transcript, whereas most non-coding RNA transcription relies on …
cis-and trans-Acting determinants of transcription termination by yeast RNA polymerase II
EJ Steinmetz, SBH Ng, JP Cloute… - Molecular and cellular …, 2006 - Am Soc Microbiol
Most eukaryotic genes are transcribed by RNA polymerase II (Pol II), including those that
produce mRNAs and many noncoding functional RNAs. Proper expression of these genes …
produce mRNAs and many noncoding functional RNAs. Proper expression of these genes …
Transcription termination by nuclear RNA polymerases
P Richard, JL Manley - Genes & development, 2009 - genesdev.cshlp.org
Gene transcription in the cell nucleus is a complex and highly regulated process.
Transcription in eukaryotes requires three distinct RNA polymerases, each of which employs …
Transcription in eukaryotes requires three distinct RNA polymerases, each of which employs …
[HTML][HTML] Transcriptomes of six mutants in the Sen1 pathway reveal combinatorial control of transcription termination across the Saccharomyces cerevisiae genome
Transcriptome studies on eukaryotic cells have revealed an unexpected abundance and
diversity of noncoding RNAs synthesized by RNA polymerase II (Pol II), some of which …
diversity of noncoding RNAs synthesized by RNA polymerase II (Pol II), some of which …