Immunity and fibrogenesis: the role of Th17/IL-17 axis in HBV and HCV-induced chronic hepatitis and progression to cirrhosis
FC Paquissi - Frontiers in Immunology, 2017 - frontiersin.org
Cirrhosis is a common final pathway for most chronic liver diseases; representing an
increasing burden worldwide and is associated with increased morbidity and mortality …
increasing burden worldwide and is associated with increased morbidity and mortality …
[PDF][PDF] Pathological functions of interleukin‐22 in chronic liver inflammation and fibrosis with hepatitis B virus infection by promoting T helper 17 cell recruitment
It is well established that interleukin (IL)‐22 has hepatoprotective and antifibrotic functions in
acute liver injury models; however, its function in patients with liver fibrosis and liver cirrhosis …
acute liver injury models; however, its function in patients with liver fibrosis and liver cirrhosis …
Pivotal roles of the interleukin‐23/T helper 17 cell axis in hepatitis B
Z Huang, JC van Velkinburgh, B Ni, Y Wu - Liver International, 2012 - Wiley Online Library
Abstract T helper 17 (Th17) cells are a newly identified subset of T helper cells that play
important roles in host defense against extracellular bacteria, as well as in the pathogenesis …
important roles in host defense against extracellular bacteria, as well as in the pathogenesis …
Increased Th1, Th17 and pro-fibrotic responses in hepatitis C-infected patients are down-regulated after 12 weeks of treatment with pegylated interferon plus ribavirin
MA Jimenez-Sousa, R Almansa, C de la Fuente… - European Cytokine …, 2010 - jle.com
Hepatitis C virus causes significant morbidity and mortality worldwide. The infection induces
upregulation of cytokine and chemokines commonly linked to the development of cellular …
upregulation of cytokine and chemokines commonly linked to the development of cellular …
Immunopathobiology and therapeutic targets related to cytokines in liver diseases
Chronic liver injury with any etiology can progress to fibrosis and the end-stage diseases
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …
Type 3 cytokines IL-17A and IL-22 drive TGF-β–dependent liver fibrosis
T Fabre, MF Molina, G Soucy, JP Goulet… - Science …, 2018 - science.org
Inflammatory immune cells can modulate activation of hepatic stellate cells (HSCs) and
progression of liver fibrosis. Type 3 inflammation characterized by production of interleukin …
progression of liver fibrosis. Type 3 inflammation characterized by production of interleukin …
Type 3 cytokines in liver fibrosis and liver cancer
MF Molina, MN Abdelnabi, T Fabre, NH Shoukry - Cytokine, 2019 - Elsevier
The type 3 cytokines IL-17 and IL-22 play a crucial, well synchronized physiological role in
wound healing and repairing tissue damage due to infections or injury at barrier surfaces …
wound healing and repairing tissue damage due to infections or injury at barrier surfaces …
Elevated TGF-β1/IL-31 pathway is associated with the disease severity of hepatitis B virus–related liver cirrhosis
D Ming, X Yu, R Guo, Y Deng, J Li, C Lin, M Su… - Viral …, 2015 - liebertpub.com
The proinflammatory cytokines transforming growth factor beta 1 (TGF-β1) and interleukin
(IL)-31 have been implicated in tissue injury. However, whether TGF-β1/IL-31 are stimulated …
(IL)-31 have been implicated in tissue injury. However, whether TGF-β1/IL-31 are stimulated …
A deleterious role for Th9/IL-9 in hepatic fibrogenesis
S Qin, D Lu, X Guo, W Luo, B Hu, X Huang, M Chen… - Scientific Reports, 2016 - nature.com
Abstract T helper 9 (Th9) cells, a recently recognized Th cell subset, are involved in
autoimmune diseases. We aimed to investigate the role of Th9/interleukin-9 (IL-9) in the …
autoimmune diseases. We aimed to investigate the role of Th9/interleukin-9 (IL-9) in the …
[HTML][HTML] Group 2 innate lymphoid cells exhibit progressively higher levels of activation during worsening of liver fibrosis
V Gonzalez-Polo, M Pucci-Molineris, V Cervera… - Annals of hepatology, 2019 - Elsevier
Abstract Introduction The interleukin-33/interleukin-13 pathway is involved in the
immunopathology of liver fibrosis and recently characterized group 2 innate lymphoid cells …
immunopathology of liver fibrosis and recently characterized group 2 innate lymphoid cells …