AtT-20 cells, which make and release beta-endorphin, or AtT-20/hENK cells, an AtT-20 cell
line transfected with the human proenkephalin gene and secreting enkephalin as well as …

AtT-20 cells, which produce ß-endorphin, and AtT-20/hENK cells, which are AtT-20 cells
transfected with a proenkephalin gene, were implanted in the rat spinal subarachnoid space …

B16 F1C29 melanoma cells, which are thought to contain and release catecholamines, were
implanted in mouse and rat spinal subarachnoid space. B16 F1C29 cell implants …

For optimal neural transplantation using gene engineering, it might be important to control
the expression of the transfected gene extrinsically as required. This strategy could be very …

We have reported that transplantation of adrenal medullary chromaffin cells that release
endogenous opioid peptides into pain modulatory regions in the CNS produce significant …

Transplantation of adrenal medullary tissue for terminal cancer pain has been tested
clinically, but this approach is not practical for routine use because of the shortage of organ …

✓ The purpose of this study was to assess whether xenogeneic tumor cells immunologically
isolated in polymer capsules could survive and continue to reduce pain when transplanted …

Chronic neuropathic pain is a common symptom in clinical practice and patients with chronic
pain are subject to a greatly impaired quality of life. Grafted genetically-modified cells …

Transplants of adrenal medullary tissue or isolated chromaffin cells into the spinal cord
subarachnoid space has been shown to reduce pain sensitivity in rats. This analgesia …

The purpose of this study was to assess whether xenogeneic tumor cells secreting β-
endorphin and immunologically isolated in polymer capsules could survive and continue to …