[HTML][HTML] Lumbar transplants of immortalized serotonergic neurons alleviate chronic neuropathic pain
MJ Eaton, DI Santiago, HA Dancausse, SR Whittemore - Pain, 1997 - Elsevier
The RN46A cell line was derived from embryonic day 13 rat medullary raphe cells by
infection with a retrovirus encoding the temperature-sensitive mutant of SV40 large T …
infection with a retrovirus encoding the temperature-sensitive mutant of SV40 large T …
Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation
Abstract Interleukin 10 (IL-10) is antinociceptive in various animal models of pain without
induction of tolerance, and its mechanism of action was generally believed to be mediated …
induction of tolerance, and its mechanism of action was generally believed to be mediated …
Ultrastructural evidence that substance P neurons form synapses with noradrenergic neurons in the A7 catecholamine cell group that modulate nociception
HK Proudfit, M Monsen - Neuroscience, 1999 - Elsevier
Potent antinociception can be produced by electrical stimulation of spinally projecting
noradrenergic neurons in the A7 catecholamine cell group and this effect is blocked by …
noradrenergic neurons in the A7 catecholamine cell group and this effect is blocked by …
Long-term alleviation of allodynia-like behaviors by intrathecal implantation of bovine chromaffin cells in rats with spinal cord injury
W Yu, JX Hao, XJ Xu, J Saydoff, A Haegerstrand… - Pain, 1998 - Elsevier
Adrenal chromaffin cells produce analgesic substances, such as catecholamines and
enkephalins, and intrathecal (it) implantation of either allografted adrenal tissue or …
enkephalins, and intrathecal (it) implantation of either allografted adrenal tissue or …
Acute antinociceptive tolerance and asymmetric cross-tolerance between endomorphin-1 and endomorphin-2 given intracerebroventricularly in the mouse
H Wu, K Hung, H Mizoguchi, JM Fujimoto… - Journal of Pharmacology …, 2001 - ASPET
Development of tolerance in mice pretreated intracerebroventricularly with μ-opioid receptor
agonist endomorphin-1, endomorphin-2, or [d-Ala2, N-Me-Phe4, Gly-ol5]-enkephalin …
agonist endomorphin-1, endomorphin-2, or [d-Ala2, N-Me-Phe4, Gly-ol5]-enkephalin …
Intrathecal polymer-encapsulated bovine adrenal chromaffin cells fail to produce analgesic effects in the hotplate and formalin test
MD Lindner, JM Francis, JA Saydoff - Experimental neurology, 2000 - Elsevier
Numerous publications have reported that adrenal chromaffin cells implanted in the lumbar
intrathecal space produce analgesic effects in rodent models of pain. The present study was …
intrathecal space produce analgesic effects in rodent models of pain. The present study was …
Nociceptive facilitating neurons in the rostral ventromedial medulla
MJ Neubert, W Kincaid, MM Heinricher - Pain, 2004 - Elsevier
The role of the periaqueductal gray-rostral ventromedial medulla (RVM) system in
descending inhibition of nociception has been studied for over 30 years. The neural basis …
descending inhibition of nociception has been studied for over 30 years. The neural basis …
Chronic morphine-treated sensory ganglion neurons remain supersensitive to the excitatory effects of naloxone for months after return to normal culture medium: an in …
SM Crain, KF Shen - Brain research, 1995 - Elsevier
Chronic morphine-treated dorsal-root ganglion (DRG) neurons in DRG/spinal cord explant
cultures were previously shown to become supersensitive to the excitatory effects of …
cultures were previously shown to become supersensitive to the excitatory effects of …
Increased levels of Met-enkephalin-like immunoreactivity in the spinal cord CSF of rats with adrenal medullary transplants
J Sagen, JE Kemmler - Brain research, 1989 - Elsevier
Recent work in our laboratory has demonstrated that the transplantation of adrenal
medullary tissue into the spinal cord subarachnoid space can reduce pain sensitivity …
medullary tissue into the spinal cord subarachnoid space can reduce pain sensitivity …
Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model
J Sagen, H Wang, GD Pappas - Pain, 1990 - Elsevier
Previous work in this laboratory has indicated that the transplantation of adrenal medullary
tissue into the subarachnoid space of the rat spinal cord can reduce pain sensitivity to acute …
tissue into the subarachnoid space of the rat spinal cord can reduce pain sensitivity to acute …