New insights into the brain involvement in patients with Crohn's disease: a voxel‐based morphometry study

A Agostini, F Benuzzi, N Filippini… - …, 2013 - Wiley Online Library
Background Crohn's disease (CD) is a chronic intestinal disorder characterized by
overproduction of inflammatory cytokines and recurrent abdominal pain. Recently, brain …

[HTML][HTML] Altered markers of brain development in Crohn's Disease with extraintestinal manifestations–a pilot study

AK Thomann, PA Thomann, RC Wolf, D Hirjak… - PloS one, 2016 - journals.plos.org
Background and Objective Alterations of brain morphology in Crohn's disease have been
reported, but data is scarce and heterogenous and the possible impact of disease …

[HTML][HTML] Structural imaging changes and behavioral correlates in patients with Crohn's disease in remission

VA Nair, P Beniwal-Patel, I Mbah, BM Young… - Frontiers in Human …, 2016 - frontiersin.org
Background: Crohn's disease (CD) is a subtype of inflammatory bowel disease caused by
immune-mediated inflammation in the gastrointestinal tract. The extent of morphologic brain …

Inflammatory bowel disease: perspectives from cingulate cortex in the first brain

BA Vogt - Neurogastroenterology & Motility, 2013 - Wiley Online Library
The article by Agostini et al.(2013) in this issue of Neurogastroenterology and Motility
evaluated patients with Crohn's disease (CD) for volumetric changes throughout the brain …

Differential brain structural and functional patterns in Crohn's disease patients are associated with different disease stages

A Agostini, F Benuzzi, D Ballotta… - Inflammatory Bowel …, 2023 - academic.oup.com
Background Crohn's disease (CD) is an inflammatory, chronic disorder that alternates
between a quiescent phase and inflammatory flare-ups. Research has begun to elucidate …

Structural and functional changes in the brain of patients with Crohn's disease: an activation likelihood estimation meta-analysis

AWK Yeung - Brain Imaging and Behavior, 2021 - Springer
Multiple reports for brain functional and structural alterations in patients with Crohn's disease
(CD) were published. The current study aimed to meta-analyze the existing neuroimaging …

Difference in regional neural fluctuations and functional connectivity in Crohn's disease: a resting-state functional MRI study

C Bao, P Liu, H Liu, X Jin, Y Shi, L Wu, X Zeng… - Brain imaging and …, 2018 - Springer
Patients with Crohn's disease (CD) are shown to have abnormal changes in brain structures.
This study aimed to further investigate whether these patients have abnormal brain activities …

Regional gray matter volume changes in brains of patients with ulcerative colitis

S Zhang, F Chen, J Wu, C Liu, G Yang… - Inflammatory Bowel …, 2022 - academic.oup.com
Background Ulcerative colitis (UC) and Crohn's disease (CD) are 2 subtypes of inflammatory
bowel disease (IBD). Several studies have reported brain abnormalities in IBD patients. This …

Exploring joint patterns of brain structure and function in inflammatory bowel diseases using multimodal data fusion

AK Thomann, MM Schmitgen, D Kmuche… - …, 2021 - Wiley Online Library
Background A growing number of neuroimaging studies suggest distinct neural changes in
inflammatory bowel diseases (IBDs). Whether such changes may show similar spatial …

Alterations in Brain Grey Matter Structures in Patients With Crohn's Disease and Their Correlation With Psychological Distress☆

CH Bao, P Liu, HR Liu, LY Wu, Y Shi… - Journal of Crohn's …, 2015 - academic.oup.com
Abstract Background: Whether Crohn's disease [CD] is correlated with brain structural
changes is unclear. This study examined changes in grey matter [GM] structures in CD …