Abstract Crohn's disease (CD), a chronic inflammatory bowel disease, involved in brain
structural and functional changes, including the amygdala. Amygdala is a key structure in …

Background and aims Inflammatory bowel disease (IBD), mainly categorized into Crohn's
disease (CD) and ulcerative colitis (UC), is a chronic relapsing gastrointestinal disorder that …

Background Behavioral symptoms, including mood disorders, substantially impact the
quality of life of patients with inflammatory bowel disease (IBD), even when clinical …

Background Crohn's disease (CD) is characterized by repetitive phases of remission and
exacerbation, the quality of life of patients with CD is strongly influenced by disease activity …

Regional cortical thickness alterations have been reported in many chronic inflammatory
and painful conditions, including inflammatory bowel diseases (IBD) and irritable bowel …

Psychological factors and comorbidities play an important role in inflammatory bowel
diseases. Such comorbidity could be associated with a specific neural phenotype. Brain …

Despite recent advances, there is still a major need to better understand the interactions
between brain function and chronic gut inflammation and its clinical implications. Alterations …

Patients with mild chronic inflammation of the rectum or ileum have reduced perceptual
responses to rectosigmoid distension compared to patients with irritable bowel syndrome …

Central nervous system (CNS) complications or manifestations of inflammatory bowel
disease deserve particular attention because symptomatic conditions can require early …

Previous studies have found neural alterations in regions involved in cognitive and affective
functions among Crohn's disease (CD) patients. The present work recruited 18 CD patients …